Efficacy of a modified cranial closure technique with bone cement in reducing postoperative complications following microvascular decompression surgery: a retrospective cohort study

Abstract Background This study aimed to assess the efficacy of a modified cranial closure technique combined with bone cement in mitigating postoperative complications, particularly cerebrospinal fluid (CSF) leakage, following microvascular decompression (MVD) surgery. Methods A retrospective analys...

Full description

Saved in:
Bibliographic Details
Main Authors: Shilong Wang, Jun Li, Jiangtao Dong, Ganggang Wang, Haoxiang Xu, Licang Zhu, Lina Pan, Hui Xu
Format: Article
Language:English
Published: BMC 2025-08-01
Series:European Journal of Medical Research
Subjects:
Online Access:https://doi.org/10.1186/s40001-025-02970-0
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849766388688748544
author Shilong Wang
Jun Li
Jiangtao Dong
Ganggang Wang
Haoxiang Xu
Licang Zhu
Lina Pan
Hui Xu
author_facet Shilong Wang
Jun Li
Jiangtao Dong
Ganggang Wang
Haoxiang Xu
Licang Zhu
Lina Pan
Hui Xu
author_sort Shilong Wang
collection DOAJ
description Abstract Background This study aimed to assess the efficacy of a modified cranial closure technique combined with bone cement in mitigating postoperative complications, particularly cerebrospinal fluid (CSF) leakage, following microvascular decompression (MVD) surgery. Methods A retrospective analysis was conducted on 234 patients who underwent MVD surgery at our institution from October 2017 to October 2024. The patients were divided into three groups based on closure methods: autologous bone with bone cement and titanium screw and plate (ABBC + TSP), autologous bone with bone cement (ABBC), and traditional cranial closure (TCC). Postoperative complications, including CSF leakage, intracranial infection, and subcutaneous effusion, were compared among the groups. Results The incidence of CSF leakage was significantly lower in the modified groups (ABBC + TSP and ABBC) compared to the traditional group (2.5% and 1.8 vs. 27.0%, P < 0.001). Multivariate logistic regression analysis confirmed that the modified technique was an independent protective factor against CSF leakage (OR 0.138, p = 0.024). Additionally, the modified groups demonstrated significantly lower rates of intracranial infection, subcutaneous effusion, and postoperative headache (p < 0.05). Conclusion The modified cranial closure technique combined with bone cement significantly reducing postoperative complications in MVD surgery, particularly CSF leakage and intracranial infection, presenting a promising approach for optimizing surgical outcomes.
format Article
id doaj-art-75c67d40303e47e1965d45e0293365c4
institution DOAJ
issn 2047-783X
language English
publishDate 2025-08-01
publisher BMC
record_format Article
series European Journal of Medical Research
spelling doaj-art-75c67d40303e47e1965d45e0293365c42025-08-20T03:04:36ZengBMCEuropean Journal of Medical Research2047-783X2025-08-0130111010.1186/s40001-025-02970-0Efficacy of a modified cranial closure technique with bone cement in reducing postoperative complications following microvascular decompression surgery: a retrospective cohort studyShilong Wang0Jun Li1Jiangtao Dong2Ganggang Wang3Haoxiang Xu4Licang Zhu5Lina Pan6Hui Xu7Department of Neurosurgery, The First Affiliated Hospital of Shihezi UniversityDepartment of Dermatology, The First Affiliated Hospital of Shihezi UniversityDepartment of Neurosurgery, The First Affiliated Hospital of Shihezi UniversityDepartment of Neurosurgery, The First Affiliated Hospital of Shihezi UniversityDepartment of Neurosurgery, The First Affiliated Hospital of Shihezi UniversityDepartment of Neurosurgery, The First Affiliated Hospital of Shihezi UniversityDepartment of Neurosurgery, The First Affiliated Hospital of Shihezi UniversityDepartment of Neurosurgery, The First Affiliated Hospital of Shihezi UniversityAbstract Background This study aimed to assess the efficacy of a modified cranial closure technique combined with bone cement in mitigating postoperative complications, particularly cerebrospinal fluid (CSF) leakage, following microvascular decompression (MVD) surgery. Methods A retrospective analysis was conducted on 234 patients who underwent MVD surgery at our institution from October 2017 to October 2024. The patients were divided into three groups based on closure methods: autologous bone with bone cement and titanium screw and plate (ABBC + TSP), autologous bone with bone cement (ABBC), and traditional cranial closure (TCC). Postoperative complications, including CSF leakage, intracranial infection, and subcutaneous effusion, were compared among the groups. Results The incidence of CSF leakage was significantly lower in the modified groups (ABBC + TSP and ABBC) compared to the traditional group (2.5% and 1.8 vs. 27.0%, P < 0.001). Multivariate logistic regression analysis confirmed that the modified technique was an independent protective factor against CSF leakage (OR 0.138, p = 0.024). Additionally, the modified groups demonstrated significantly lower rates of intracranial infection, subcutaneous effusion, and postoperative headache (p < 0.05). Conclusion The modified cranial closure technique combined with bone cement significantly reducing postoperative complications in MVD surgery, particularly CSF leakage and intracranial infection, presenting a promising approach for optimizing surgical outcomes.https://doi.org/10.1186/s40001-025-02970-0Modified cranial closure techniqueBone cementPostoperative complicationsMicrovascular decompressionCSF leakageIntracranial infection
spellingShingle Shilong Wang
Jun Li
Jiangtao Dong
Ganggang Wang
Haoxiang Xu
Licang Zhu
Lina Pan
Hui Xu
Efficacy of a modified cranial closure technique with bone cement in reducing postoperative complications following microvascular decompression surgery: a retrospective cohort study
European Journal of Medical Research
Modified cranial closure technique
Bone cement
Postoperative complications
Microvascular decompression
CSF leakage
Intracranial infection
title Efficacy of a modified cranial closure technique with bone cement in reducing postoperative complications following microvascular decompression surgery: a retrospective cohort study
title_full Efficacy of a modified cranial closure technique with bone cement in reducing postoperative complications following microvascular decompression surgery: a retrospective cohort study
title_fullStr Efficacy of a modified cranial closure technique with bone cement in reducing postoperative complications following microvascular decompression surgery: a retrospective cohort study
title_full_unstemmed Efficacy of a modified cranial closure technique with bone cement in reducing postoperative complications following microvascular decompression surgery: a retrospective cohort study
title_short Efficacy of a modified cranial closure technique with bone cement in reducing postoperative complications following microvascular decompression surgery: a retrospective cohort study
title_sort efficacy of a modified cranial closure technique with bone cement in reducing postoperative complications following microvascular decompression surgery a retrospective cohort study
topic Modified cranial closure technique
Bone cement
Postoperative complications
Microvascular decompression
CSF leakage
Intracranial infection
url https://doi.org/10.1186/s40001-025-02970-0
work_keys_str_mv AT shilongwang efficacyofamodifiedcranialclosuretechniquewithbonecementinreducingpostoperativecomplicationsfollowingmicrovasculardecompressionsurgeryaretrospectivecohortstudy
AT junli efficacyofamodifiedcranialclosuretechniquewithbonecementinreducingpostoperativecomplicationsfollowingmicrovasculardecompressionsurgeryaretrospectivecohortstudy
AT jiangtaodong efficacyofamodifiedcranialclosuretechniquewithbonecementinreducingpostoperativecomplicationsfollowingmicrovasculardecompressionsurgeryaretrospectivecohortstudy
AT ganggangwang efficacyofamodifiedcranialclosuretechniquewithbonecementinreducingpostoperativecomplicationsfollowingmicrovasculardecompressionsurgeryaretrospectivecohortstudy
AT haoxiangxu efficacyofamodifiedcranialclosuretechniquewithbonecementinreducingpostoperativecomplicationsfollowingmicrovasculardecompressionsurgeryaretrospectivecohortstudy
AT licangzhu efficacyofamodifiedcranialclosuretechniquewithbonecementinreducingpostoperativecomplicationsfollowingmicrovasculardecompressionsurgeryaretrospectivecohortstudy
AT linapan efficacyofamodifiedcranialclosuretechniquewithbonecementinreducingpostoperativecomplicationsfollowingmicrovasculardecompressionsurgeryaretrospectivecohortstudy
AT huixu efficacyofamodifiedcranialclosuretechniquewithbonecementinreducingpostoperativecomplicationsfollowingmicrovasculardecompressionsurgeryaretrospectivecohortstudy