Case studies in heritable vascular disease: Proceedings of the UTHealth Houston Multidisciplinary Aortic Conference
Heritable thoracic aortic disease is caused by dominantly inherited mutations in more than a dozen genes, including TGFB2 mutations that cause Loeys-Dietz syndrome. McGovern Medical School at UTHealth Houston convenes a regular conference that includes cardiothoracic and vascular surgeons, cardiolog...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-02-01
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| Series: | Journal of Vascular Surgery Cases and Innovative Techniques |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2468428724002685 |
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| author | Milan Jaiswal, BA Lucas Ribe, MD Rana O. Afifi, MD Yuki Ikeno, MD Alana C. Cecchi, MS Bihong Zhao, MD, PhD Akiko Tanaka, MD, PhD Gustavo S. Oderich, MD L. Maximilian Buja, MD Dianna M. Milewicz, MD, PhD Siddharth K. Prakash, MD, PhD Anthony L. Estrera, MD |
| author_facet | Milan Jaiswal, BA Lucas Ribe, MD Rana O. Afifi, MD Yuki Ikeno, MD Alana C. Cecchi, MS Bihong Zhao, MD, PhD Akiko Tanaka, MD, PhD Gustavo S. Oderich, MD L. Maximilian Buja, MD Dianna M. Milewicz, MD, PhD Siddharth K. Prakash, MD, PhD Anthony L. Estrera, MD |
| author_sort | Milan Jaiswal, BA |
| collection | DOAJ |
| description | Heritable thoracic aortic disease is caused by dominantly inherited mutations in more than a dozen genes, including TGFB2 mutations that cause Loeys-Dietz syndrome. McGovern Medical School at UTHealth Houston convenes a regular conference that includes cardiothoracic and vascular surgeons, cardiologists, geneticists, radiologists, and pathologists to formulate multidisciplinary approaches for the management of complex heritable thoracic aortic disease cases. In this report, we highlight the unique management of individuals with distinct presentations of Loeys-Dietz syndrome owing to TGFB2 mutations. |
| format | Article |
| id | doaj-art-75b83d31542644e69dfd7e299121a31f |
| institution | Kabale University |
| issn | 2468-4287 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Vascular Surgery Cases and Innovative Techniques |
| spelling | doaj-art-75b83d31542644e69dfd7e299121a31f2025-01-20T04:17:46ZengElsevierJournal of Vascular Surgery Cases and Innovative Techniques2468-42872025-02-01111101684Case studies in heritable vascular disease: Proceedings of the UTHealth Houston Multidisciplinary Aortic ConferenceMilan Jaiswal, BA0Lucas Ribe, MD1Rana O. Afifi, MD2Yuki Ikeno, MD3Alana C. Cecchi, MS4Bihong Zhao, MD, PhD5Akiko Tanaka, MD, PhD6Gustavo S. Oderich, MD7L. Maximilian Buja, MD8Dianna M. Milewicz, MD, PhD9Siddharth K. Prakash, MD, PhD10Anthony L. Estrera, MD11Division of Medical Genetics, Department of Internal Medicine, McGovern Medical School at UTHealth Houston, Houston, TX; Division of Cardiology, Department of Internal Medicine, McGovern Medical School at UTHealth Houston, Houston, TXDepartment of Cardiothoracic and Vascular Surgery, McGovern Medical School at UTHealth Houston, Houston, TXDepartment of Cardiothoracic and Vascular Surgery, McGovern Medical School at UTHealth Houston, Houston, TX; Correspondence: Rana O. Afifi, MD Associate Professor, Vascular Surgery, Department of Cardiothoracic and Vascular Surgery, McGovern Medical School at UTHealth Houston, 6400 Fannin St, Ste #2850, Houston, TX 77030Department of Cardiothoracic and Vascular Surgery, McGovern Medical School at UTHealth Houston, Houston, TXDivision of Medical Genetics, Department of Internal Medicine, McGovern Medical School at UTHealth Houston, Houston, TXDepartment of Pathology and Laboratory Medicine, McGovern Medical School at UTHealth Houston, Houston, TXDepartment of Cardiothoracic and Vascular Surgery, McGovern Medical School at UTHealth Houston, Houston, TXDepartment of Cardiothoracic and Vascular Surgery, McGovern Medical School at UTHealth Houston, Houston, TXDepartment of Pathology and Laboratory Medicine, McGovern Medical School at UTHealth Houston, Houston, TXDivision of Medical Genetics, Department of Internal Medicine, McGovern Medical School at UTHealth Houston, Houston, TXDivision of Medical Genetics, Department of Internal Medicine, McGovern Medical School at UTHealth Houston, Houston, TX; Division of Cardiology, Department of Internal Medicine, McGovern Medical School at UTHealth Houston, Houston, TXDepartment of Cardiothoracic and Vascular Surgery, McGovern Medical School at UTHealth Houston, Houston, TXHeritable thoracic aortic disease is caused by dominantly inherited mutations in more than a dozen genes, including TGFB2 mutations that cause Loeys-Dietz syndrome. McGovern Medical School at UTHealth Houston convenes a regular conference that includes cardiothoracic and vascular surgeons, cardiologists, geneticists, radiologists, and pathologists to formulate multidisciplinary approaches for the management of complex heritable thoracic aortic disease cases. In this report, we highlight the unique management of individuals with distinct presentations of Loeys-Dietz syndrome owing to TGFB2 mutations.http://www.sciencedirect.com/science/article/pii/S2468428724002685Heritable thoracic aortic diseasesHTADTGFB2Loeys-Dietz syndromeLDSGenetic testing |
| spellingShingle | Milan Jaiswal, BA Lucas Ribe, MD Rana O. Afifi, MD Yuki Ikeno, MD Alana C. Cecchi, MS Bihong Zhao, MD, PhD Akiko Tanaka, MD, PhD Gustavo S. Oderich, MD L. Maximilian Buja, MD Dianna M. Milewicz, MD, PhD Siddharth K. Prakash, MD, PhD Anthony L. Estrera, MD Case studies in heritable vascular disease: Proceedings of the UTHealth Houston Multidisciplinary Aortic Conference Journal of Vascular Surgery Cases and Innovative Techniques Heritable thoracic aortic diseases HTAD TGFB2 Loeys-Dietz syndrome LDS Genetic testing |
| title | Case studies in heritable vascular disease: Proceedings of the UTHealth Houston Multidisciplinary Aortic Conference |
| title_full | Case studies in heritable vascular disease: Proceedings of the UTHealth Houston Multidisciplinary Aortic Conference |
| title_fullStr | Case studies in heritable vascular disease: Proceedings of the UTHealth Houston Multidisciplinary Aortic Conference |
| title_full_unstemmed | Case studies in heritable vascular disease: Proceedings of the UTHealth Houston Multidisciplinary Aortic Conference |
| title_short | Case studies in heritable vascular disease: Proceedings of the UTHealth Houston Multidisciplinary Aortic Conference |
| title_sort | case studies in heritable vascular disease proceedings of the uthealth houston multidisciplinary aortic conference |
| topic | Heritable thoracic aortic diseases HTAD TGFB2 Loeys-Dietz syndrome LDS Genetic testing |
| url | http://www.sciencedirect.com/science/article/pii/S2468428724002685 |
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