Synthesis and Biological Evaluation of 2,4-Diaminoquinazolines as Potential Antitumor Agents

In the present study, a set of 2-anilino-4-alkylaminoquinazoline derivatives were synthesized and tested for their antitumor activities in vitro against a panel of four human cancer cell lines and for their DNA-binding affinity. Among the synthesized compounds, 4c and 5b with 4-substitution at the p...

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Bibliographic Details
Main Authors: Mohammad A. Alassaf, Khalid B. Selim, Magda N. A. Nasr
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2022/7763545
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