Synthesis and Biological Evaluation of 2,4-Diaminoquinazolines as Potential Antitumor Agents
In the present study, a set of 2-anilino-4-alkylaminoquinazoline derivatives were synthesized and tested for their antitumor activities in vitro against a panel of four human cancer cell lines and for their DNA-binding affinity. Among the synthesized compounds, 4c and 5b with 4-substitution at the p...
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Main Authors: | Mohammad A. Alassaf, Khalid B. Selim, Magda N. A. Nasr |
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Format: | Article |
Language: | English |
Published: |
Wiley
2022-01-01
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Series: | Journal of Chemistry |
Online Access: | http://dx.doi.org/10.1155/2022/7763545 |
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