Influence of Dietary Factors on Helicobacter pylori and CagA Seroprevalence in Bulgaria
The aim of this study was to assess the association between some dietary factors and prevalence of H. pylori infection or strain virulence in 294 adult asymptomatic blood donors. Methods. Seroprevalence was evaluated using ELISA. Logistic regression was used. Results. Anti-H. pylori IgG prevalence w...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2017/9212143 |
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| author | Daniel Yordanov Lyudmila Boyanova Rumyana Markovska Juliana Ilieva Nikolay Andreev Galina Gergova Ivan Mitov |
| author_facet | Daniel Yordanov Lyudmila Boyanova Rumyana Markovska Juliana Ilieva Nikolay Andreev Galina Gergova Ivan Mitov |
| author_sort | Daniel Yordanov |
| collection | DOAJ |
| description | The aim of this study was to assess the association between some dietary factors and prevalence of H. pylori infection or strain virulence in 294 adult asymptomatic blood donors. Methods. Seroprevalence was evaluated using ELISA. Logistic regression was used. Results. Anti-H. pylori IgG prevalence was 72.4%, and CagA IgG seroprevalence was 49.3%. In the multivariate analyses, the frequent (>5 days per week) honey consumption was associated with both reduced H. pylori seroprevalence OR, 0.68 with 95% confidence interval (CI), 0.473–0.967 and reduced CagA IgG seroprevalence OR, 0.65 with 95% CI, 0.486–0859. Frequent (>5 days per week) yoghurt consumption also was associated with lower H. pylori virulence of the strains (CagA IgG OR, 0.56 with 95% CI, 0.341–0.921). Smoking and consumption of the other dietary factors resulted in no significant differences in the prevalence of H. pylori IgG and CagA IgG within the subject groups. Conclusion. To the best of our knowledge, this is the first report revealing reverse associations between honey or yoghurt consumption and CagA IgG prevalence as well as between frequent honey consumption and lower prevalence of the H. pylori infection. Regular honey and yoghurt consumption can be of value as a supplement in the control of H. pylori therapy. |
| format | Article |
| id | doaj-art-7540e7e9eef74a4bba0592e311362c21 |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-7540e7e9eef74a4bba0592e311362c212025-02-03T01:09:31ZengWileyGastroenterology Research and Practice1687-61211687-630X2017-01-01201710.1155/2017/92121439212143Influence of Dietary Factors on Helicobacter pylori and CagA Seroprevalence in BulgariaDaniel Yordanov0Lyudmila Boyanova1Rumyana Markovska2Juliana Ilieva3Nikolay Andreev4Galina Gergova5Ivan Mitov6Department of Medical Microbiology, Medical University of Sofia, Sofia, BulgariaDepartment of Medical Microbiology, Medical University of Sofia, Sofia, BulgariaDepartment of Medical Microbiology, Medical University of Sofia, Sofia, BulgariaDepartment of Social Medicine and Healthcare Management, Medical University of Sofia, Sofia, BulgariaCentre of Transfusion Hematology, “St. Anna” University Hospital, Sofia, BulgariaDepartment of Medical Microbiology, Medical University of Sofia, Sofia, BulgariaDepartment of Medical Microbiology, Medical University of Sofia, Sofia, BulgariaThe aim of this study was to assess the association between some dietary factors and prevalence of H. pylori infection or strain virulence in 294 adult asymptomatic blood donors. Methods. Seroprevalence was evaluated using ELISA. Logistic regression was used. Results. Anti-H. pylori IgG prevalence was 72.4%, and CagA IgG seroprevalence was 49.3%. In the multivariate analyses, the frequent (>5 days per week) honey consumption was associated with both reduced H. pylori seroprevalence OR, 0.68 with 95% confidence interval (CI), 0.473–0.967 and reduced CagA IgG seroprevalence OR, 0.65 with 95% CI, 0.486–0859. Frequent (>5 days per week) yoghurt consumption also was associated with lower H. pylori virulence of the strains (CagA IgG OR, 0.56 with 95% CI, 0.341–0.921). Smoking and consumption of the other dietary factors resulted in no significant differences in the prevalence of H. pylori IgG and CagA IgG within the subject groups. Conclusion. To the best of our knowledge, this is the first report revealing reverse associations between honey or yoghurt consumption and CagA IgG prevalence as well as between frequent honey consumption and lower prevalence of the H. pylori infection. Regular honey and yoghurt consumption can be of value as a supplement in the control of H. pylori therapy.http://dx.doi.org/10.1155/2017/9212143 |
| spellingShingle | Daniel Yordanov Lyudmila Boyanova Rumyana Markovska Juliana Ilieva Nikolay Andreev Galina Gergova Ivan Mitov Influence of Dietary Factors on Helicobacter pylori and CagA Seroprevalence in Bulgaria Gastroenterology Research and Practice |
| title | Influence of Dietary Factors on Helicobacter pylori and CagA Seroprevalence in Bulgaria |
| title_full | Influence of Dietary Factors on Helicobacter pylori and CagA Seroprevalence in Bulgaria |
| title_fullStr | Influence of Dietary Factors on Helicobacter pylori and CagA Seroprevalence in Bulgaria |
| title_full_unstemmed | Influence of Dietary Factors on Helicobacter pylori and CagA Seroprevalence in Bulgaria |
| title_short | Influence of Dietary Factors on Helicobacter pylori and CagA Seroprevalence in Bulgaria |
| title_sort | influence of dietary factors on helicobacter pylori and caga seroprevalence in bulgaria |
| url | http://dx.doi.org/10.1155/2017/9212143 |
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