Fate and long-lasting therapeutic effects of mesenchymal stromal/stem-like cells: mechanistic insights

Fate and long-lasting therapeutic effects of mesenchymal stromal/stem-like cells: mechanistic insights

Abstract A large body of evidence suggests that mesenchymal stromal cells (MSCs) are able to respond rapidly to the cytokine milieu following systemic infusion. This encounter has the potential to dictate their therapeutic efficacy (also referred to as licensing). MSCs are able to rapidly react to c...

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Bibliographic Details
Main Authors: Akram Hoseinzadeh, Seyed-Alireza Esmaeili, Reza Sahebi, Anahita Madani Melak, Mahmoud Mahmoudi, Maliheh Hasannia, Rasoul Baharlou
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cells
Apoptosis
Efferocytosis
Apoptotic bodies
Long-term effectiveness
Immunoregulation
Online Access:https://doi.org/10.1186/s13287-025-04158-z
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