Intratympanic administration of dexamethasone attenuates radiation induced damage to middle ear mucosa

Intratympanic administration of dexamethasone attenuates radiation induced damage to middle ear mucosa

Abstract Radiotherapy (RTx) is a highly effective treatment for head and neck cancer that can cause concurrent damage to surrounding healthy tissues. In cases of nasopharyngeal carcinoma (NPC), the auditory apparatus is inevitably exposed to radiation fields and sustains considerable damage, resulti...

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Bibliographic Details
Main Authors: Hyuk Chan Kwon, Sup Kim, Sheng Jin, Sun-Ae Shin, Jeong Han Lee, Min Jung Park, Soo Jeong Kim, Yong-Ho Park
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Radiotherapy
Middle ear
Eustachian tube
Epithelial cells
Dexamethasone
Intratympanic injection
Online Access:https://doi.org/10.1038/s41598-025-87195-1
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