Computational analysis of Annona muricata phytochemicals for targeted modulation of endocrine networks in polycystic ovary syndrome

Computational analysis of Annona muricata phytochemicals for targeted modulation of endocrine networks in polycystic ovary syndrome

Abstract Polycystic ovarian syndrome (PCOS) is a complex reproductive disorder involving dysfunction across multiple hormonal pathways. Current pharmaceutical treatments use a simplistic single-target approach and overlook molecular interactions. This study provides a novel computational perspective...

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Main Authors: Babatunji Emmanuel Oyinloye, Oluwaseun Emmanuel Agboola, Aderonke Moyosola Ayeni, Oluwatoyin Mary Oyinloye, Samuel Sunday Agboola, Olajumoke Tolulope Idowu, Makhosazana Siduduzile Mathenjwa-Goqo, Olutunmise Victoria Owolabi, Bolajoko Idiat Ogunyinka, Foluso Oluwagbemiga Osunsanmi, Basiru Olaitan Ajiboye, Olaposi Idowu Omotuyi
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Discover Food
Subjects:
Polycystic ovarian syndrome (PCOS)
Annona muricata
Multi-receptor targeting
Hormonal imbalance
Online Access:https://doi.org/10.1007/s44187-025-00441-3
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