Principal Components Analysis of Spot Urine Caffeine and Caffeine Metabolites Identifies Promising Exposure Biomarkers of Caffeine and Theobromine Intake in a Cross-Sectional Survey of the United States Population (National Health and Nutrition Examination Survey 2009–2014)

Background: Spot urine concentrations of caffeine and certain caffeine metabolites correlate well with 24-h caffeine intake and have potential use as caffeine exposure biomarkers. However, a high degree of intercorrelation exists among these urine compounds, and their correlations with intake are ve...

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Bibliographic Details
Main Authors: Ching-I Pao, Michael E Rybak, Maya R Sternberg
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Current Developments in Nutrition
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Online Access:http://www.sciencedirect.com/science/article/pii/S2475299125029014
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