CaF2 nanoparticles deliver siRNA targeting STAT6 and PPAR- γ to depolarise tumour-associated macrophages
Breast cancer is a leading cause of death in women, partly due to challenges posed by constituents of the tumour-microenvironment, such as tumour-associated macrophages (TAMs). Polarisation of macrophages to a pro-tumour phenotype usually involves STAT6 and PPAR- γ pathways. In this study, CaF2 nano...
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| Main Authors: | Hamed Al-Busaidi, Won Fen Wong, Lakshmi Selvaratnam, Ezharul Hoque Chowdhury |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-01-01
|
| Series: | BBA Advances |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S266716032500033X |
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