Case Report: Remission of a patient with complex combination of autoimmune diseases by anti-CD19 CAR-T cell therapy

Case Report: Remission of a patient with complex combination of autoimmune diseases by anti-CD19 CAR-T cell therapy

CAR−T cell therapy has been proven effective in various autoimmune diseases, with most studies utilizing lentiviral‐transduced CAR−T cells. In recent years, retroviral vector−transduced CAR−T cells—characterized by a high positivity rate, stable cell lines, and lower plasmid requirements—have attrac...

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Bibliographic Details
Main Authors:	Xudong Liu, Wenxiang Zhu, Nan Su, Yanyi Ma, Fang Wang, Jingyi Xu, Heyang Zhang, Xiaomeng Luo, Yuetong Zhao, Jianxun Wang, Yuanyuan Shi, Yishuo Li, Pingting Yang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-08-01
Series:	Frontiers in Immunology
Subjects:	autoimmunity systemic lupus erythematosus antiphospholipid syndrome type B insulin resistance syndrome anti-CD19 CAR-T
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1645304/full
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