Protocol for predicting suppressors of cell-death pathways based on transcriptomic and vulnerability data

Summary: Here, we present a computational protocol for predicting repressors of cancer cell death by combining vulnerability and transcriptomic responses to cell death inducers. We describe steps for calculating a set of predictors for each gene and aggregating them into a single metric, ranking the...

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Bibliographic Details
Main Authors: Yaron Vinik, Avi Maimon, Sima Lev
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:STAR Protocols
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666166725002618
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