Chronic Q Fever with Vascular Involvement: Progressive Abdominal Pain in a Patient with Aortic Aneurysm Repair in the United States
Q fever is a zoonotic bacterial infection caused by Coxiella burnetii. Chronic Q fever comprises less than five percent of all Q fever cases and, of those, endocarditis is the most common presentation (up to 78% of cases), followed by vascular involvement. Risk factors for chronic Q fever with vascu...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2019/5369707 |
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| author | Zanthia Wiley Sujan Reddy Kara M. Jacobs Slifka David C. Brandon John Jernigan Gilbert J. Kersh Paige A. Armstrong |
| author_facet | Zanthia Wiley Sujan Reddy Kara M. Jacobs Slifka David C. Brandon John Jernigan Gilbert J. Kersh Paige A. Armstrong |
| author_sort | Zanthia Wiley |
| collection | DOAJ |
| description | Q fever is a zoonotic bacterial infection caused by Coxiella burnetii. Chronic Q fever comprises less than five percent of all Q fever cases and, of those, endocarditis is the most common presentation (up to 78% of cases), followed by vascular involvement. Risk factors for chronic Q fever with vascular involvement include previous vascular surgery, preexisting valvular defects, aneurysms, and vascular prostheses. The most common symptoms of chronic Q fever with vascular involvement are nonspecific, including weight loss, fatigue, and abdominal pain. Criteria for diagnosis of chronic Q fever include clinical evidence of infection and laboratory criteria (antibody detection, detection of Coxiella burnetii DNA, or growth in culture). Treatment of chronic Q fever with vascular involvement includes a prolonged course of doxycycline and hydroxychloroquine (≥18 months) as well as early surgical intervention, which has been shown to improve survival. Mortality is high in untreated chronic Q fever. We report a case of chronic Q fever with vascular involvement in a 77-year-old man with prior infrarenal aortic aneurysm repair, who lived near a livestock farm in the southeastern United States. |
| format | Article |
| id | doaj-art-74b4ce6562ba403c8f59f703438d0d0c |
| institution | Kabale University |
| issn | 2090-6625 2090-6633 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-74b4ce6562ba403c8f59f703438d0d0c2025-02-03T01:23:41ZengWileyCase Reports in Infectious Diseases2090-66252090-66332019-01-01201910.1155/2019/53697075369707Chronic Q Fever with Vascular Involvement: Progressive Abdominal Pain in a Patient with Aortic Aneurysm Repair in the United StatesZanthia Wiley0Sujan Reddy1Kara M. Jacobs Slifka2David C. Brandon3John Jernigan4Gilbert J. Kersh5Paige A. Armstrong6Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USADivision of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USADivision of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USADepartment of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, USADivision of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USARickettsial Zoonoses Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USARickettsial Zoonoses Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USAQ fever is a zoonotic bacterial infection caused by Coxiella burnetii. Chronic Q fever comprises less than five percent of all Q fever cases and, of those, endocarditis is the most common presentation (up to 78% of cases), followed by vascular involvement. Risk factors for chronic Q fever with vascular involvement include previous vascular surgery, preexisting valvular defects, aneurysms, and vascular prostheses. The most common symptoms of chronic Q fever with vascular involvement are nonspecific, including weight loss, fatigue, and abdominal pain. Criteria for diagnosis of chronic Q fever include clinical evidence of infection and laboratory criteria (antibody detection, detection of Coxiella burnetii DNA, or growth in culture). Treatment of chronic Q fever with vascular involvement includes a prolonged course of doxycycline and hydroxychloroquine (≥18 months) as well as early surgical intervention, which has been shown to improve survival. Mortality is high in untreated chronic Q fever. We report a case of chronic Q fever with vascular involvement in a 77-year-old man with prior infrarenal aortic aneurysm repair, who lived near a livestock farm in the southeastern United States.http://dx.doi.org/10.1155/2019/5369707 |
| spellingShingle | Zanthia Wiley Sujan Reddy Kara M. Jacobs Slifka David C. Brandon John Jernigan Gilbert J. Kersh Paige A. Armstrong Chronic Q Fever with Vascular Involvement: Progressive Abdominal Pain in a Patient with Aortic Aneurysm Repair in the United States Case Reports in Infectious Diseases |
| title | Chronic Q Fever with Vascular Involvement: Progressive Abdominal Pain in a Patient with Aortic Aneurysm Repair in the United States |
| title_full | Chronic Q Fever with Vascular Involvement: Progressive Abdominal Pain in a Patient with Aortic Aneurysm Repair in the United States |
| title_fullStr | Chronic Q Fever with Vascular Involvement: Progressive Abdominal Pain in a Patient with Aortic Aneurysm Repair in the United States |
| title_full_unstemmed | Chronic Q Fever with Vascular Involvement: Progressive Abdominal Pain in a Patient with Aortic Aneurysm Repair in the United States |
| title_short | Chronic Q Fever with Vascular Involvement: Progressive Abdominal Pain in a Patient with Aortic Aneurysm Repair in the United States |
| title_sort | chronic q fever with vascular involvement progressive abdominal pain in a patient with aortic aneurysm repair in the united states |
| url | http://dx.doi.org/10.1155/2019/5369707 |
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