CHARACTERISTIC CHANGES IN THE COPY NUMBER OF INTERSPERSED REPEATS IN BONE MARROW CELLS OF MICE TREATED WITH CYCLOPHOSPHAMIDE AND EXOGENOUS HUMAN DNA

CHARACTERISTIC CHANGES IN THE COPY NUMBER OF INTERSPERSED REPEATS IN BONE MARROW CELLS OF MICE TREATED WITH CYCLOPHOSPHAMIDE AND EXOGENOUS HUMAN DNA

Mice were observed to get sick and die upon administration of exogenous DNA in a specific period of time following their pretreatment with the cytostatic cyclophosphamide (CP) (Dolgova et al., 2011). It was established that exogenous DNA reaches internal compartments of bone marrow cells (BMCs) wher...

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Main Authors: E. V. Dolgova, A. V. Prokopenko, V. P. Nikolin, N. A. Popova, A. S. Proskurina, K. E. Orishchenko, E. A. Alyamkina, Ya. R. Efremov, E. R. Chernykh, A. A. Ostanin, S. S. Bogachev, T. S. Gvozdeva, E. M. Malkova, O. S. Taranov, V. A. Rogachev, A. V. Panov, S. N. Zagrebelnyi, M. A. Shurdov
Format: Article
Language:English
Published: Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders 2014-12-01
Series:Вавиловский журнал генетики и селекции
Subjects:
cyclophosphamide
exogenous dna
interstrand cross-links
short interspersed repeat (sine)
homologous recombination
Online Access:https://vavilov.elpub.ru/jour/article/view/147
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