Squamous Cell Carcinoma Developing in a Cutaneous Lichen Planus Lesion: A Rare Case
Lichen planus is a benign disorder characterized by an itchy, noninfectious skin rash. Though lichen planus is a common papulosquamous disorder affecting about 1-2% of the population, neoplastic transformation of cutaneous lichen planus lesions occurs very rarely and should be borne in mind while tr...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Dermatological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2014/205638 |
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| author | Saptarshi Ghosh Sivasankar Kotne P. B. Ananda Rao S. P. V. Turlapati Dillip Kumar Soren |
| author_facet | Saptarshi Ghosh Sivasankar Kotne P. B. Ananda Rao S. P. V. Turlapati Dillip Kumar Soren |
| author_sort | Saptarshi Ghosh |
| collection | DOAJ |
| description | Lichen planus is a benign disorder characterized by an itchy, noninfectious skin rash. Though lichen planus is a common papulosquamous disorder affecting about 1-2% of the population, neoplastic transformation of cutaneous lichen planus lesions occurs very rarely and should be borne in mind while treating nonhealing longstanding lesions of lichen planus. Studies suggest an estimated 0.3–3% risk of malignancy in patients with oral lichen planus, however, cutaneous lichen planus does not carry an increased risk of malignant degeneration. We present a case of a 36-year-old male with a 10-year-long history of hypertrophic lichen planus who presented with a nonhealing ulcer in the left popliteal fossa. The patient underwent wide local excision with superficial skin grafting. Postoperative histopathological examination revealed verrucous squamous cell carcinoma complicating lichen planus. In view of underlying structure involvement, adjuvant radiation therapy was given. This case is being reported to emphasize the infrequent possibility of development of malignancy in cutaneous lichen planus, especially if it presents as a longstanding, nonhealing, itchy lesion with patchy areas of depigmentation in the lower limbs. |
| format | Article |
| id | doaj-art-746e20be893c4145bfd28923bf2eef67 |
| institution | Kabale University |
| issn | 2090-6463 2090-6471 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dermatological Medicine |
| spelling | doaj-art-746e20be893c4145bfd28923bf2eef672025-02-03T01:33:25ZengWileyCase Reports in Dermatological Medicine2090-64632090-64712014-01-01201410.1155/2014/205638205638Squamous Cell Carcinoma Developing in a Cutaneous Lichen Planus Lesion: A Rare CaseSaptarshi Ghosh0Sivasankar Kotne1P. B. Ananda Rao2S. P. V. Turlapati3Dillip Kumar Soren4Department of Radiotherapy, GSL Medical College & General Hospital, Opposite to Swatantra Hospital, Near Kambala Park, Rajahmundry, Andhra Pradesh 533105, IndiaDepartment of Radiotherapy, GSL Medical College & General Hospital, Opposite to Swatantra Hospital, Near Kambala Park, Rajahmundry, Andhra Pradesh 533105, IndiaDepartment of Radiotherapy, GSL Medical College & General Hospital, Opposite to Swatantra Hospital, Near Kambala Park, Rajahmundry, Andhra Pradesh 533105, IndiaDepartment of Pathology, GSL Medical College & General Hospital, Rajahmundry, Andhra Pradesh 533296, IndiaDepartment of Surgery, GSL Medical College & General Hospital, Rajahmundry, Andhra Pradesh 533296, IndiaLichen planus is a benign disorder characterized by an itchy, noninfectious skin rash. Though lichen planus is a common papulosquamous disorder affecting about 1-2% of the population, neoplastic transformation of cutaneous lichen planus lesions occurs very rarely and should be borne in mind while treating nonhealing longstanding lesions of lichen planus. Studies suggest an estimated 0.3–3% risk of malignancy in patients with oral lichen planus, however, cutaneous lichen planus does not carry an increased risk of malignant degeneration. We present a case of a 36-year-old male with a 10-year-long history of hypertrophic lichen planus who presented with a nonhealing ulcer in the left popliteal fossa. The patient underwent wide local excision with superficial skin grafting. Postoperative histopathological examination revealed verrucous squamous cell carcinoma complicating lichen planus. In view of underlying structure involvement, adjuvant radiation therapy was given. This case is being reported to emphasize the infrequent possibility of development of malignancy in cutaneous lichen planus, especially if it presents as a longstanding, nonhealing, itchy lesion with patchy areas of depigmentation in the lower limbs.http://dx.doi.org/10.1155/2014/205638 |
| spellingShingle | Saptarshi Ghosh Sivasankar Kotne P. B. Ananda Rao S. P. V. Turlapati Dillip Kumar Soren Squamous Cell Carcinoma Developing in a Cutaneous Lichen Planus Lesion: A Rare Case Case Reports in Dermatological Medicine |
| title | Squamous Cell Carcinoma Developing in a Cutaneous Lichen Planus Lesion: A Rare Case |
| title_full | Squamous Cell Carcinoma Developing in a Cutaneous Lichen Planus Lesion: A Rare Case |
| title_fullStr | Squamous Cell Carcinoma Developing in a Cutaneous Lichen Planus Lesion: A Rare Case |
| title_full_unstemmed | Squamous Cell Carcinoma Developing in a Cutaneous Lichen Planus Lesion: A Rare Case |
| title_short | Squamous Cell Carcinoma Developing in a Cutaneous Lichen Planus Lesion: A Rare Case |
| title_sort | squamous cell carcinoma developing in a cutaneous lichen planus lesion a rare case |
| url | http://dx.doi.org/10.1155/2014/205638 |
| work_keys_str_mv | AT saptarshighosh squamouscellcarcinomadevelopinginacutaneouslichenplanuslesionararecase AT sivasankarkotne squamouscellcarcinomadevelopinginacutaneouslichenplanuslesionararecase AT pbanandarao squamouscellcarcinomadevelopinginacutaneouslichenplanuslesionararecase AT spvturlapati squamouscellcarcinomadevelopinginacutaneouslichenplanuslesionararecase AT dillipkumarsoren squamouscellcarcinomadevelopinginacutaneouslichenplanuslesionararecase |