The Mitochondrial Disulfide Relay System: Roles in Oxidative Protein Folding and Beyond
Disulfide bond formation drives protein import of most proteins of the mitochondrial intermembrane space (IMS). The main components of this disulfide relay machinery are the oxidoreductase Mia40 and the sulfhydryl oxidase Erv1/ALR. Their precise functions have been elucidated in molecular detail for...
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Main Authors: | Manuel Fischer, Jan Riemer |
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Format: | Article |
Language: | English |
Published: |
Wiley
2013-01-01
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Series: | International Journal of Cell Biology |
Online Access: | http://dx.doi.org/10.1155/2013/742923 |
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