COMPARISON OF REACTOGENICITY AND IMMUNOGENICITY OF LIVE VACCINES AGAINST INFECTIOUS LARYNGOTRACHEITIS
Humoral immune response and ciliary activity of tracheal mucosa of poultry, vaccinated against infectious laryngotracheitis using ciliostatic test, was studied. Regardless of the vaccination route the vaccines decreased the ciliary activity by 5–9 % on Days 3 to 7 post vaccination. Herewith the vacc...
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Da Vinci Media
2018-05-01
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Online Access: | https://veterinary.arriah.ru/jour/article/view/342 |
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author | S. A. Pokhvalny M. S. Kukushkina V. Yu. Kulakov N. V. Moroz N. A. Perevozchikova |
author_facet | S. A. Pokhvalny M. S. Kukushkina V. Yu. Kulakov N. V. Moroz N. A. Perevozchikova |
author_sort | S. A. Pokhvalny |
collection | DOAJ |
description | Humoral immune response and ciliary activity of tracheal mucosa of poultry, vaccinated against infectious laryngotracheitis using ciliostatic test, was studied. Regardless of the vaccination route the vaccines decreased the ciliary activity by 5–9 % on Days 3 to 7 post vaccination. Herewith the vaccine ocular application in some chicks induced oneeye serous conjunctivitis, which resolved subsequently. Oral vaccination did not cause any clinical changes. Serological monitoring revealed an earlier and stronger immunity in poultry vaccinated by ocular route. The required seroprotection level in test groups was higher than the minimal value (80%) starting from Day 16 post vaccination. The period of immunity development after oral vaccination correlated with the vaccine dose volume. Moreover the domestic vaccine was highly competitive with foreign vaccines in immunogenicity and reactogenicity. |
format | Article |
id | doaj-art-743974e205ba40f298f96f56ead814b9 |
institution | Kabale University |
issn | 2304-196X 2658-6959 |
language | English |
publishDate | 2018-05-01 |
publisher | Da Vinci Media |
record_format | Article |
series | Ветеринария сегодня |
spelling | doaj-art-743974e205ba40f298f96f56ead814b92025-02-06T09:52:06ZengDa Vinci MediaВетеринария сегодня2304-196X2658-69592018-05-0101192510.29326/2304-196X-2018-1-19-22342COMPARISON OF REACTOGENICITY AND IMMUNOGENICITY OF LIVE VACCINES AGAINST INFECTIOUS LARYNGOTRACHEITISS. A. Pokhvalny0M. S. Kukushkina1V. Yu. Kulakov2N. V. Moroz3N. A. Perevozchikova4FGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirHumoral immune response and ciliary activity of tracheal mucosa of poultry, vaccinated against infectious laryngotracheitis using ciliostatic test, was studied. Regardless of the vaccination route the vaccines decreased the ciliary activity by 5–9 % on Days 3 to 7 post vaccination. Herewith the vaccine ocular application in some chicks induced oneeye serous conjunctivitis, which resolved subsequently. Oral vaccination did not cause any clinical changes. Serological monitoring revealed an earlier and stronger immunity in poultry vaccinated by ocular route. The required seroprotection level in test groups was higher than the minimal value (80%) starting from Day 16 post vaccination. The period of immunity development after oral vaccination correlated with the vaccine dose volume. Moreover the domestic vaccine was highly competitive with foreign vaccines in immunogenicity and reactogenicity.https://veterinary.arriah.ru/jour/article/view/342infectious laryngotracheitisreactogenicityciliostatic testseroconversion |
spellingShingle | S. A. Pokhvalny M. S. Kukushkina V. Yu. Kulakov N. V. Moroz N. A. Perevozchikova COMPARISON OF REACTOGENICITY AND IMMUNOGENICITY OF LIVE VACCINES AGAINST INFECTIOUS LARYNGOTRACHEITIS Ветеринария сегодня infectious laryngotracheitis reactogenicity ciliostatic test seroconversion |
title | COMPARISON OF REACTOGENICITY AND IMMUNOGENICITY OF LIVE VACCINES AGAINST INFECTIOUS LARYNGOTRACHEITIS |
title_full | COMPARISON OF REACTOGENICITY AND IMMUNOGENICITY OF LIVE VACCINES AGAINST INFECTIOUS LARYNGOTRACHEITIS |
title_fullStr | COMPARISON OF REACTOGENICITY AND IMMUNOGENICITY OF LIVE VACCINES AGAINST INFECTIOUS LARYNGOTRACHEITIS |
title_full_unstemmed | COMPARISON OF REACTOGENICITY AND IMMUNOGENICITY OF LIVE VACCINES AGAINST INFECTIOUS LARYNGOTRACHEITIS |
title_short | COMPARISON OF REACTOGENICITY AND IMMUNOGENICITY OF LIVE VACCINES AGAINST INFECTIOUS LARYNGOTRACHEITIS |
title_sort | comparison of reactogenicity and immunogenicity of live vaccines against infectious laryngotracheitis |
topic | infectious laryngotracheitis reactogenicity ciliostatic test seroconversion |
url | https://veterinary.arriah.ru/jour/article/view/342 |
work_keys_str_mv | AT sapokhvalny comparisonofreactogenicityandimmunogenicityoflivevaccinesagainstinfectiouslaryngotracheitis AT mskukushkina comparisonofreactogenicityandimmunogenicityoflivevaccinesagainstinfectiouslaryngotracheitis AT vyukulakov comparisonofreactogenicityandimmunogenicityoflivevaccinesagainstinfectiouslaryngotracheitis AT nvmoroz comparisonofreactogenicityandimmunogenicityoflivevaccinesagainstinfectiouslaryngotracheitis AT naperevozchikova comparisonofreactogenicityandimmunogenicityoflivevaccinesagainstinfectiouslaryngotracheitis |