COMPARISON OF REACTOGENICITY AND IMMUNOGENICITY OF LIVE VACCINES AGAINST INFECTIOUS LARYNGOTRACHEITIS

Humoral immune response and ciliary activity of tracheal mucosa of poultry, vaccinated against infectious laryngotracheitis using ciliostatic test, was studied. Regardless of the vaccination route the vaccines decreased the ciliary activity by 5–9 % on Days 3 to 7 post vaccination. Herewith the vacc...

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Main Authors: S. A. Pokhvalny, M. S. Kukushkina, V. Yu. Kulakov, N. V. Moroz, N. A. Perevozchikova
Format: Article
Language:English
Published: Da Vinci Media 2018-05-01
Series:Ветеринария сегодня
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Online Access:https://veterinary.arriah.ru/jour/article/view/342
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author S. A. Pokhvalny
M. S. Kukushkina
V. Yu. Kulakov
N. V. Moroz
N. A. Perevozchikova
author_facet S. A. Pokhvalny
M. S. Kukushkina
V. Yu. Kulakov
N. V. Moroz
N. A. Perevozchikova
author_sort S. A. Pokhvalny
collection DOAJ
description Humoral immune response and ciliary activity of tracheal mucosa of poultry, vaccinated against infectious laryngotracheitis using ciliostatic test, was studied. Regardless of the vaccination route the vaccines decreased the ciliary activity by 5–9 % on Days 3 to 7 post vaccination. Herewith the vaccine ocular application in some chicks induced oneeye serous conjunctivitis, which resolved subsequently. Oral vaccination did not cause any clinical changes. Serological monitoring revealed an earlier and stronger immunity in poultry vaccinated by ocular route. The required seroprotection level in test groups was higher than the minimal value (80%) starting from Day 16 post vaccination. The period of immunity development after oral vaccination correlated with the vaccine dose volume. Moreover the domestic vaccine was highly competitive with foreign vaccines in immunogenicity and reactogenicity.
format Article
id doaj-art-743974e205ba40f298f96f56ead814b9
institution Kabale University
issn 2304-196X
2658-6959
language English
publishDate 2018-05-01
publisher Da Vinci Media
record_format Article
series Ветеринария сегодня
spelling doaj-art-743974e205ba40f298f96f56ead814b92025-02-06T09:52:06ZengDa Vinci MediaВетеринария сегодня2304-196X2658-69592018-05-0101192510.29326/2304-196X-2018-1-19-22342COMPARISON OF REACTOGENICITY AND IMMUNOGENICITY OF LIVE VACCINES AGAINST INFECTIOUS LARYNGOTRACHEITISS. A. Pokhvalny0M. S. Kukushkina1V. Yu. Kulakov2N. V. Moroz3N. A. Perevozchikova4FGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirHumoral immune response and ciliary activity of tracheal mucosa of poultry, vaccinated against infectious laryngotracheitis using ciliostatic test, was studied. Regardless of the vaccination route the vaccines decreased the ciliary activity by 5–9 % on Days 3 to 7 post vaccination. Herewith the vaccine ocular application in some chicks induced oneeye serous conjunctivitis, which resolved subsequently. Oral vaccination did not cause any clinical changes. Serological monitoring revealed an earlier and stronger immunity in poultry vaccinated by ocular route. The required seroprotection level in test groups was higher than the minimal value (80%) starting from Day 16 post vaccination. The period of immunity development after oral vaccination correlated with the vaccine dose volume. Moreover the domestic vaccine was highly competitive with foreign vaccines in immunogenicity and reactogenicity.https://veterinary.arriah.ru/jour/article/view/342infectious laryngotracheitisreactogenicityciliostatic testseroconversion
spellingShingle S. A. Pokhvalny
M. S. Kukushkina
V. Yu. Kulakov
N. V. Moroz
N. A. Perevozchikova
COMPARISON OF REACTOGENICITY AND IMMUNOGENICITY OF LIVE VACCINES AGAINST INFECTIOUS LARYNGOTRACHEITIS
Ветеринария сегодня
infectious laryngotracheitis
reactogenicity
ciliostatic test
seroconversion
title COMPARISON OF REACTOGENICITY AND IMMUNOGENICITY OF LIVE VACCINES AGAINST INFECTIOUS LARYNGOTRACHEITIS
title_full COMPARISON OF REACTOGENICITY AND IMMUNOGENICITY OF LIVE VACCINES AGAINST INFECTIOUS LARYNGOTRACHEITIS
title_fullStr COMPARISON OF REACTOGENICITY AND IMMUNOGENICITY OF LIVE VACCINES AGAINST INFECTIOUS LARYNGOTRACHEITIS
title_full_unstemmed COMPARISON OF REACTOGENICITY AND IMMUNOGENICITY OF LIVE VACCINES AGAINST INFECTIOUS LARYNGOTRACHEITIS
title_short COMPARISON OF REACTOGENICITY AND IMMUNOGENICITY OF LIVE VACCINES AGAINST INFECTIOUS LARYNGOTRACHEITIS
title_sort comparison of reactogenicity and immunogenicity of live vaccines against infectious laryngotracheitis
topic infectious laryngotracheitis
reactogenicity
ciliostatic test
seroconversion
url https://veterinary.arriah.ru/jour/article/view/342
work_keys_str_mv AT sapokhvalny comparisonofreactogenicityandimmunogenicityoflivevaccinesagainstinfectiouslaryngotracheitis
AT mskukushkina comparisonofreactogenicityandimmunogenicityoflivevaccinesagainstinfectiouslaryngotracheitis
AT vyukulakov comparisonofreactogenicityandimmunogenicityoflivevaccinesagainstinfectiouslaryngotracheitis
AT nvmoroz comparisonofreactogenicityandimmunogenicityoflivevaccinesagainstinfectiouslaryngotracheitis
AT naperevozchikova comparisonofreactogenicityandimmunogenicityoflivevaccinesagainstinfectiouslaryngotracheitis