Determination of Alkaloids and Flavonoids in Sophora flavescens by UHPLC-Q-TOF/MS
This study is based on UHPLC-Q-TOF/MS and fragment ions to achieve classification and identification of alkaloids and flavonoids in Sophora flavescens. By reviewing the available and relevant literature, the mass fragmentation rules of alkaloids and flavonoids were summarized. 0.1% formic acid water...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Journal of Analytical Methods in Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2021/9915027 |
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| author | Yaqian Dong Guoxiang Jia Jingwen Hu Hui Liu Tingting Wu Shenshen Yang Yubo Li Ting Cai |
| author_facet | Yaqian Dong Guoxiang Jia Jingwen Hu Hui Liu Tingting Wu Shenshen Yang Yubo Li Ting Cai |
| author_sort | Yaqian Dong |
| collection | DOAJ |
| description | This study is based on UHPLC-Q-TOF/MS and fragment ions to achieve classification and identification of alkaloids and flavonoids in Sophora flavescens. By reviewing the available and relevant literature, the mass fragmentation rules of alkaloids and flavonoids were summarized. 0.1% formic acid water (A) and acetonitrile (B) were used as mobile phases. 37 chemical constituents were identified, including 13 alkaloids and 24 flavonoids. This research method offers a complete strategy based on the fragmentation information of characteristic fragment ions and neutral loss obtained by MS/MS to characterize the chemical composition of Sophora flavescens. |
| format | Article |
| id | doaj-art-742c1b5b71fb4d9ba3b2b72db99aecbf |
| institution | Kabale University |
| issn | 2090-8865 2090-8873 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Analytical Methods in Chemistry |
| spelling | doaj-art-742c1b5b71fb4d9ba3b2b72db99aecbf2025-02-03T01:25:13ZengWileyJournal of Analytical Methods in Chemistry2090-88652090-88732021-01-01202110.1155/2021/99150279915027Determination of Alkaloids and Flavonoids in Sophora flavescens by UHPLC-Q-TOF/MSYaqian Dong0Guoxiang Jia1Jingwen Hu2Hui Liu3Tingting Wu4Shenshen Yang5Yubo Li6Ting Cai7School of Traditional Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, No. 10 Poyang Lake Road, Tuanbo New City, Jinghai District, Tianjin 301617, ChinaSchool of Traditional Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, No. 10 Poyang Lake Road, Tuanbo New City, Jinghai District, Tianjin 301617, ChinaSchool of Traditional Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, No. 10 Poyang Lake Road, Tuanbo New City, Jinghai District, Tianjin 301617, ChinaSchool of Traditional Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, No. 10 Poyang Lake Road, Tuanbo New City, Jinghai District, Tianjin 301617, ChinaSchool of Traditional Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, No. 10 Poyang Lake Road, Tuanbo New City, Jinghai District, Tianjin 301617, ChinaSchool of Traditional Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, No. 10 Poyang Lake Road, Tuanbo New City, Jinghai District, Tianjin 301617, ChinaSchool of Traditional Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, No. 10 Poyang Lake Road, Tuanbo New City, Jinghai District, Tianjin 301617, ChinaHwa Mei Hospital, University of Chinese Academy of Sciences (Ningbo No. 2 Hospital), Ningbo 315010, ChinaThis study is based on UHPLC-Q-TOF/MS and fragment ions to achieve classification and identification of alkaloids and flavonoids in Sophora flavescens. By reviewing the available and relevant literature, the mass fragmentation rules of alkaloids and flavonoids were summarized. 0.1% formic acid water (A) and acetonitrile (B) were used as mobile phases. 37 chemical constituents were identified, including 13 alkaloids and 24 flavonoids. This research method offers a complete strategy based on the fragmentation information of characteristic fragment ions and neutral loss obtained by MS/MS to characterize the chemical composition of Sophora flavescens.http://dx.doi.org/10.1155/2021/9915027 |
| spellingShingle | Yaqian Dong Guoxiang Jia Jingwen Hu Hui Liu Tingting Wu Shenshen Yang Yubo Li Ting Cai Determination of Alkaloids and Flavonoids in Sophora flavescens by UHPLC-Q-TOF/MS Journal of Analytical Methods in Chemistry |
| title | Determination of Alkaloids and Flavonoids in Sophora flavescens by UHPLC-Q-TOF/MS |
| title_full | Determination of Alkaloids and Flavonoids in Sophora flavescens by UHPLC-Q-TOF/MS |
| title_fullStr | Determination of Alkaloids and Flavonoids in Sophora flavescens by UHPLC-Q-TOF/MS |
| title_full_unstemmed | Determination of Alkaloids and Flavonoids in Sophora flavescens by UHPLC-Q-TOF/MS |
| title_short | Determination of Alkaloids and Flavonoids in Sophora flavescens by UHPLC-Q-TOF/MS |
| title_sort | determination of alkaloids and flavonoids in sophora flavescens by uhplc q tof ms |
| url | http://dx.doi.org/10.1155/2021/9915027 |
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