Cancer Antigen 125 during Pregnancy in Women without Ovarian Tumor Is Not Often Rising
Objective. To determine the percentage of rising serum cancer antigen (CA-125) in singleton pregnant women whose ultrasonographical findings were normal. Methods. Singleton pregnant women who received antenatal care at our institute with a normal ultrasonographical examination in their first and/or...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Obstetrics and Gynecology International |
| Online Access: | http://dx.doi.org/10.1155/2018/8141583 |
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| author | Rattapon Amampai Prapaporn Suprasert |
| author_facet | Rattapon Amampai Prapaporn Suprasert |
| author_sort | Rattapon Amampai |
| collection | DOAJ |
| description | Objective. To determine the percentage of rising serum cancer antigen (CA-125) in singleton pregnant women whose ultrasonographical findings were normal. Methods. Singleton pregnant women who received antenatal care at our institute with a normal ultrasonographical examination in their first and/or second trimester were invited to participate in blood testing for CA-125. The conditions that might affect the CA-125 level were excluded. The normal level of CA-125 was defined as ≤35 U/ml. Results. 136 pregnant women met the inclusion criteria. Of these cases, 87 cases received a blood test for CA-125 in both their first and second trimesters while 46 and 3 cases received a blood test for CA-125 in only the first and second trimester, respectively. The median serum CA-125 levels in the first and second trimester were 16.44 (range 5.94–77.54) U/ml and 16.76 (range 5.26–35.81) U/ml, respectively. Only 9.1% of the studied patients showed an abnormal CA-125 level in the first trimester period and only one case showed an abnormal CA-125 level in the second trimester period. Conclusion. Few of normal pregnancies showed rising CA-125. Therefore, when it elevated in pregnant women, other causes such as the adnexal lesion should be investigated. |
| format | Article |
| id | doaj-art-7418df5fac1b430fa9389ffc118c1017 |
| institution | Kabale University |
| issn | 1687-9589 1687-9597 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Obstetrics and Gynecology International |
| spelling | doaj-art-7418df5fac1b430fa9389ffc118c10172025-02-03T06:15:13ZengWileyObstetrics and Gynecology International1687-95891687-95972018-01-01201810.1155/2018/81415838141583Cancer Antigen 125 during Pregnancy in Women without Ovarian Tumor Is Not Often RisingRattapon Amampai0Prapaporn Suprasert1Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandDepartment of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandObjective. To determine the percentage of rising serum cancer antigen (CA-125) in singleton pregnant women whose ultrasonographical findings were normal. Methods. Singleton pregnant women who received antenatal care at our institute with a normal ultrasonographical examination in their first and/or second trimester were invited to participate in blood testing for CA-125. The conditions that might affect the CA-125 level were excluded. The normal level of CA-125 was defined as ≤35 U/ml. Results. 136 pregnant women met the inclusion criteria. Of these cases, 87 cases received a blood test for CA-125 in both their first and second trimesters while 46 and 3 cases received a blood test for CA-125 in only the first and second trimester, respectively. The median serum CA-125 levels in the first and second trimester were 16.44 (range 5.94–77.54) U/ml and 16.76 (range 5.26–35.81) U/ml, respectively. Only 9.1% of the studied patients showed an abnormal CA-125 level in the first trimester period and only one case showed an abnormal CA-125 level in the second trimester period. Conclusion. Few of normal pregnancies showed rising CA-125. Therefore, when it elevated in pregnant women, other causes such as the adnexal lesion should be investigated.http://dx.doi.org/10.1155/2018/8141583 |
| spellingShingle | Rattapon Amampai Prapaporn Suprasert Cancer Antigen 125 during Pregnancy in Women without Ovarian Tumor Is Not Often Rising Obstetrics and Gynecology International |
| title | Cancer Antigen 125 during Pregnancy in Women without Ovarian Tumor Is Not Often Rising |
| title_full | Cancer Antigen 125 during Pregnancy in Women without Ovarian Tumor Is Not Often Rising |
| title_fullStr | Cancer Antigen 125 during Pregnancy in Women without Ovarian Tumor Is Not Often Rising |
| title_full_unstemmed | Cancer Antigen 125 during Pregnancy in Women without Ovarian Tumor Is Not Often Rising |
| title_short | Cancer Antigen 125 during Pregnancy in Women without Ovarian Tumor Is Not Often Rising |
| title_sort | cancer antigen 125 during pregnancy in women without ovarian tumor is not often rising |
| url | http://dx.doi.org/10.1155/2018/8141583 |
| work_keys_str_mv | AT rattaponamampai cancerantigen125duringpregnancyinwomenwithoutovariantumorisnotoftenrising AT prapapornsuprasert cancerantigen125duringpregnancyinwomenwithoutovariantumorisnotoftenrising |