Pharmaceutical hemostasis at peptic ulcer bleeding: state-of-the-art and perspectives
Aim of investigation. To study efficacy of parenteral proton pump inhibitors in patients with ulcerative gastroduodenal bleeding.Material and methods. Overall 71 patients were included in original study. Patients of the first group (n=30) received antisecretory treatment by parenteral omeprazole, th...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Gastro LLC
2013-07-01
|
| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| Subjects: | |
| Online Access: | https://www.gastro-j.ru/jour/article/view/1200 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1823860203665227776 |
|---|---|
| author | A. A. Schegolev O. A. Al Sabunchi S. A. Valetov A. V. Pavlychev Ye. A. Klochneva |
| author_facet | A. A. Schegolev O. A. Al Sabunchi S. A. Valetov A. V. Pavlychev Ye. A. Klochneva |
| author_sort | A. A. Schegolev |
| collection | DOAJ |
| description | Aim of investigation. To study efficacy of parenteral proton pump inhibitors in patients with ulcerative gastroduodenal bleeding.Material and methods. Overall 71 patients were included in original study. Patients of the first group (n=30) received antisecretory treatment by parenteral omeprazole, the second group (n=41) — tablet form of the same preparation.Results. In the first group no relapses of bleeding or mortality was detected, in the second group in 4 (10%) patients there was relapse of bleeding, that allows to assume higher efficacy of therapeutic hemostasis by the parenteral form of proton pump inhibitors within complex therapy.Conclusions. Application of Omez, lyophilizate for infusions, allows to improve treatment results in patients of the main group, reduces risk of hemorrhage relapse and, therefore mortality and urgent surgery rates. |
| format | Article |
| id | doaj-art-740a232b3a6e499f8372c240e099644e |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2013-07-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-740a232b3a6e499f8372c240e099644e2025-02-10T16:14:32ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732013-07-012332427784Pharmaceutical hemostasis at peptic ulcer bleeding: state-of-the-art and perspectivesA. A. Schegolev0O. A. Al Sabunchi1S. A. Valetov2A. V. Pavlychev3Ye. A. Klochneva4Pirogov Russian National Research Medical UniversityPirogov Russian National Research Medical UniversityPirogov Russian National Research Medical UniversityPirogov Russian National Research Medical UniversityPirogov Russian National Research Medical UniversityAim of investigation. To study efficacy of parenteral proton pump inhibitors in patients with ulcerative gastroduodenal bleeding.Material and methods. Overall 71 patients were included in original study. Patients of the first group (n=30) received antisecretory treatment by parenteral omeprazole, the second group (n=41) — tablet form of the same preparation.Results. In the first group no relapses of bleeding or mortality was detected, in the second group in 4 (10%) patients there was relapse of bleeding, that allows to assume higher efficacy of therapeutic hemostasis by the parenteral form of proton pump inhibitors within complex therapy.Conclusions. Application of Omez, lyophilizate for infusions, allows to improve treatment results in patients of the main group, reduces risk of hemorrhage relapse and, therefore mortality and urgent surgery rates.https://www.gastro-j.ru/jour/article/view/1200ulcerbleedinghemostasisproton pump inhibitors |
| spellingShingle | A. A. Schegolev O. A. Al Sabunchi S. A. Valetov A. V. Pavlychev Ye. A. Klochneva Pharmaceutical hemostasis at peptic ulcer bleeding: state-of-the-art and perspectives Российский журнал гастроэнтерологии, гепатологии, колопроктологии ulcer bleeding hemostasis proton pump inhibitors |
| title | Pharmaceutical hemostasis at peptic ulcer bleeding: state-of-the-art and perspectives |
| title_full | Pharmaceutical hemostasis at peptic ulcer bleeding: state-of-the-art and perspectives |
| title_fullStr | Pharmaceutical hemostasis at peptic ulcer bleeding: state-of-the-art and perspectives |
| title_full_unstemmed | Pharmaceutical hemostasis at peptic ulcer bleeding: state-of-the-art and perspectives |
| title_short | Pharmaceutical hemostasis at peptic ulcer bleeding: state-of-the-art and perspectives |
| title_sort | pharmaceutical hemostasis at peptic ulcer bleeding state of the art and perspectives |
| topic | ulcer bleeding hemostasis proton pump inhibitors |
| url | https://www.gastro-j.ru/jour/article/view/1200 |
| work_keys_str_mv | AT aaschegolev pharmaceuticalhemostasisatpepticulcerbleedingstateoftheartandperspectives AT oaalsabunchi pharmaceuticalhemostasisatpepticulcerbleedingstateoftheartandperspectives AT savaletov pharmaceuticalhemostasisatpepticulcerbleedingstateoftheartandperspectives AT avpavlychev pharmaceuticalhemostasisatpepticulcerbleedingstateoftheartandperspectives AT yeaklochneva pharmaceuticalhemostasisatpepticulcerbleedingstateoftheartandperspectives |