Optimized network inference for immune diseased single cells

Optimized network inference for immune diseased single cells

IntroductionMathematical models are powerful tools that can be used to advance our understanding of complex diseases. Autoimmune disorders such as systemic lupus erythematosus (SLE) are highly heterogeneous and require high-resolution mechanistic approaches. In this work, we present ONIDsc, a single...

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Bibliographic Details
Main Authors: Elena Merino Tejero, Dwain Jude Vaz, Guillermo Barturen, María Rivas-Torrubia, Marta E. Alarcón-Riquelme, Walter Kolch, David Matallanas
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
network inference
Systemic lupus erythematosus (SLE)
single-cell
mathematical modeling
gene marker
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1597862/full
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