Bone organoid 3D bioprinting: Construction and application in bone regeneration

Repair of critical-size bone defects remains a significant challenge. In recent years, organoid technology has emerged as a promising strategy for bone regeneration, but developing bone organoids with complex structure and function still faces many hurdles. Three-dimensional (3D) bioprinting, a revo...

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Bibliographic Details
Main Authors: Tang Zihui, Zhong Chang, Luo Jiayu, Wang Qi, Zhou Ping
Format: Article
Language:English
Published: EDP Sciences 2025-01-01
Series:BIO Web of Conferences
Online Access:https://www.bio-conferences.org/articles/bioconf/pdf/2025/25/bioconf_icbb2025_02005.pdf
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Summary:Repair of critical-size bone defects remains a significant challenge. In recent years, organoid technology has emerged as a promising strategy for bone regeneration, but developing bone organoids with complex structure and function still faces many hurdles. Three-dimensional (3D) bioprinting, a revolutionary additive manufacturing technology, can precisely deposit bioink layer by layer with a specific pattern to construct the required 3D structure, which provides a simpler and more efficient method for generating bone organoids. This review summarizes the 3D bioprinting strategies of bone organoids and their application in bone regeneration in order to provide a reference for future research.
ISSN:2117-4458