Accidental Intrathecal Injection of Tranexamic Acid

Tranexamic acid (TXA) is a popular antifibrinolytic drug that is commonly used in patients with bleeding disorder. Major morbidities and mortalities have been reported following inadvertent intrathecal injection of TXA. In this paper, inadvertent intrathecal injection of TXA has resulted from simila...

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Main Authors: Khaled Mahmoud, Amany Ammar
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Anesthesiology
Online Access:http://dx.doi.org/10.1155/2012/646028
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author Khaled Mahmoud
Amany Ammar
author_facet Khaled Mahmoud
Amany Ammar
author_sort Khaled Mahmoud
collection DOAJ
description Tranexamic acid (TXA) is a popular antifibrinolytic drug that is commonly used in patients with bleeding disorder. Major morbidities and mortalities have been reported following inadvertent intrathecal injection of TXA. In this paper, inadvertent intrathecal injection of TXA has resulted from similarities in appearance between TXA and heavy bupivacaine 0.5% ampoules. The patient experienced severe pain in the back and gluteal region upon injection in association with systemic hypertension and tachycardia followed by generalized myoclonic seizures and ventricular fibrillation.
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institution Kabale University
issn 2090-6382
2090-6390
language English
publishDate 2012-01-01
publisher Wiley
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series Case Reports in Anesthesiology
spelling doaj-art-73c6728916c7456fb2c47bb6852d94de2025-02-03T05:46:07ZengWileyCase Reports in Anesthesiology2090-63822090-63902012-01-01201210.1155/2012/646028646028Accidental Intrathecal Injection of Tranexamic AcidKhaled Mahmoud0Amany Ammar1Faculty of Medicine, Minoufiya University, Shebin El Kom, Minoufiya 32511, EgyptFaculty of Medicine, Minoufiya University, Shebin El Kom, Minoufiya 32511, EgyptTranexamic acid (TXA) is a popular antifibrinolytic drug that is commonly used in patients with bleeding disorder. Major morbidities and mortalities have been reported following inadvertent intrathecal injection of TXA. In this paper, inadvertent intrathecal injection of TXA has resulted from similarities in appearance between TXA and heavy bupivacaine 0.5% ampoules. The patient experienced severe pain in the back and gluteal region upon injection in association with systemic hypertension and tachycardia followed by generalized myoclonic seizures and ventricular fibrillation.http://dx.doi.org/10.1155/2012/646028
spellingShingle Khaled Mahmoud
Amany Ammar
Accidental Intrathecal Injection of Tranexamic Acid
Case Reports in Anesthesiology
title Accidental Intrathecal Injection of Tranexamic Acid
title_full Accidental Intrathecal Injection of Tranexamic Acid
title_fullStr Accidental Intrathecal Injection of Tranexamic Acid
title_full_unstemmed Accidental Intrathecal Injection of Tranexamic Acid
title_short Accidental Intrathecal Injection of Tranexamic Acid
title_sort accidental intrathecal injection of tranexamic acid
url http://dx.doi.org/10.1155/2012/646028
work_keys_str_mv AT khaledmahmoud accidentalintrathecalinjectionoftranexamicacid
AT amanyammar accidentalintrathecalinjectionoftranexamicacid