Unusual syphilis manifestation: From breast implant rupture to systemic erythroderma
This case report describes a rare and unusual manifestation of syphilis in a 55-year-old transgender female with a history of breast implant surgery. The patient presented with a painless enlargement of the right breast, accompanied by pruritus and skin lesions. Initial misdiagnosis led to treatment...
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| Language: | English |
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Elsevier
2025-01-01
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| Series: | IDCases |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214250925000253 |
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| author | Vivien Moris Eliott Laine Sahal Khan Leslie Ann See |
| author_facet | Vivien Moris Eliott Laine Sahal Khan Leslie Ann See |
| author_sort | Vivien Moris |
| collection | DOAJ |
| description | This case report describes a rare and unusual manifestation of syphilis in a 55-year-old transgender female with a history of breast implant surgery. The patient presented with a painless enlargement of the right breast, accompanied by pruritus and skin lesions. Initial misdiagnosis led to treatment for scabies, which worsened into diffuse erythroderma. Further examination revealed breast implant rupture and systemic lymphadenopathy. Surgical removal of the implant and seroma drainage was performed. Pathological findings showed chronic inflammation, with concerns about a cutaneous T-cell lymphoproliferative disorder, but no signs of malignancy were observed. Serological tests confirmed active syphilis with a positive TPHA titer and VDRL result. This case highlights the importance of considering infectious etiologies, such as syphilis, even in patients with atypical clinical presentations, including those involving breast implants and skin conditions. Timely diagnosis and appropriate management are critical to prevent systemic complications in similar cases. |
| format | Article |
| id | doaj-art-73b2fbb41e9e416cbb032f82be345875 |
| institution | Kabale University |
| issn | 2214-2509 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | IDCases |
| spelling | doaj-art-73b2fbb41e9e416cbb032f82be3458752025-02-05T04:32:03ZengElsevierIDCases2214-25092025-01-0139e02170Unusual syphilis manifestation: From breast implant rupture to systemic erythrodermaVivien Moris0Eliott Laine1Sahal Khan2Leslie Ann See3Department of Plastic and Reconstructive Surgery, University Hospital of Dijon, France; Correspondence to: Plastic Surgery Department, University Hospital of Dijon, 14 rue Paul Gaffarel, Dijon 21000 , France.Division of Orthopaedic Surgery and Musculoskeletal Trauma Care, University Hospital of Dijon-Burgundy, Dijon, FranceDepartment of Plastic and Reconstructive Surgery, University Hospital of Dijon, FranceDepartment of Plastic and Reconstructive Surgery, University Hospital of Dijon, FranceThis case report describes a rare and unusual manifestation of syphilis in a 55-year-old transgender female with a history of breast implant surgery. The patient presented with a painless enlargement of the right breast, accompanied by pruritus and skin lesions. Initial misdiagnosis led to treatment for scabies, which worsened into diffuse erythroderma. Further examination revealed breast implant rupture and systemic lymphadenopathy. Surgical removal of the implant and seroma drainage was performed. Pathological findings showed chronic inflammation, with concerns about a cutaneous T-cell lymphoproliferative disorder, but no signs of malignancy were observed. Serological tests confirmed active syphilis with a positive TPHA titer and VDRL result. This case highlights the importance of considering infectious etiologies, such as syphilis, even in patients with atypical clinical presentations, including those involving breast implants and skin conditions. Timely diagnosis and appropriate management are critical to prevent systemic complications in similar cases.http://www.sciencedirect.com/science/article/pii/S2214250925000253SyphilisBreast implant complicationTransgender healthErythrodermLymphadenopathy |
| spellingShingle | Vivien Moris Eliott Laine Sahal Khan Leslie Ann See Unusual syphilis manifestation: From breast implant rupture to systemic erythroderma IDCases Syphilis Breast implant complication Transgender health Erythroderm Lymphadenopathy |
| title | Unusual syphilis manifestation: From breast implant rupture to systemic erythroderma |
| title_full | Unusual syphilis manifestation: From breast implant rupture to systemic erythroderma |
| title_fullStr | Unusual syphilis manifestation: From breast implant rupture to systemic erythroderma |
| title_full_unstemmed | Unusual syphilis manifestation: From breast implant rupture to systemic erythroderma |
| title_short | Unusual syphilis manifestation: From breast implant rupture to systemic erythroderma |
| title_sort | unusual syphilis manifestation from breast implant rupture to systemic erythroderma |
| topic | Syphilis Breast implant complication Transgender health Erythroderm Lymphadenopathy |
| url | http://www.sciencedirect.com/science/article/pii/S2214250925000253 |
| work_keys_str_mv | AT vivienmoris unusualsyphilismanifestationfrombreastimplantrupturetosystemicerythroderma AT eliottlaine unusualsyphilismanifestationfrombreastimplantrupturetosystemicerythroderma AT sahalkhan unusualsyphilismanifestationfrombreastimplantrupturetosystemicerythroderma AT leslieannsee unusualsyphilismanifestationfrombreastimplantrupturetosystemicerythroderma |