Activating CD137 Signaling Promotes Sprouting Angiogenesis via Increased VEGFA Secretion and the VEGFR2/Akt/eNOS Pathway
Combination of antiangiogenesis and immunotherapy may be an effective strategy for treatment of solid tumors. Our previous work reported that activation of CD137 signaling promotes intraplaque angiogenesis. A number of studies have demonstrated that vascular endothelial growth factor receptor 2 (VEG...
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Main Authors: | Bo Li, Yue Zhang, Runting Yin, Wei Zhong, Rui Chen, Jinchuan Yan |
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Format: | Article |
Language: | English |
Published: |
Wiley
2020-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2020/1649453 |
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