Genomic and virulent characterization of a duck-associated Salmonella serovar Potsdam from China
Salmonella, a common zoonotic pathogen, is a significant concern for public health, particularly when it contaminates animal-borne products. The potential for Salmonella to infect duck embryos and disrupt their normal development not only causes substantial economic losses for the industry but also...
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Elsevier
2025-01-01
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| Series: | Poultry Science |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0032579124012240 |
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| author | Hongli An Xiamei Kang Chenhu Huang Chenghao Jia Jiaqi Chen Yingying Huang Qianzhe Cao Yan Li Biao Tang Min Yue |
| author_facet | Hongli An Xiamei Kang Chenhu Huang Chenghao Jia Jiaqi Chen Yingying Huang Qianzhe Cao Yan Li Biao Tang Min Yue |
| author_sort | Hongli An |
| collection | DOAJ |
| description | Salmonella, a common zoonotic pathogen, is a significant concern for public health, particularly when it contaminates animal-borne products. The potential for Salmonella to infect duck embryos and disrupt their normal development not only causes substantial economic losses for the industry but also poses a severe threat to public health. However, there is a lack of understanding about the prevalence of Salmonella in duck embryos and their potential public health implications. Our study aims to fill this gap by providing genomic features of the antimicrobial resistance and virulence potential of Salmonella isolates from dead duck embryos using whole-genome sequencing and in silico toolkits. We also sought to assess the virulent characterization of the major serovar isolates by experimental infection of chicken and duck embryos. Our investigation of 195 duck embryo eggs led to the isolation of 40 (20.51%) Salmonella strains, with Salmonella serovar Potsdam being the most prevalent serovar. Most isolates were resistant to streptomycin (57.3%) and nalidixic acid (50%). Notably, our findings demonstrated that S. Potsdam exhibited a preference for ducks over chickens, suggesting potential host specificity. Additionally, global phylogenomic analysis, incorporating 180 global genomes, revealed a predominant association of S. Potsdam with ducks, supporting an adaptive process specific to the waterfowl. This study determined Salmonella serovars and antimicrobial resistance profiles in dead duck embryos, revealing a rare Salmonella serovar Potsdam with a potential for duck adaption. |
| format | Article |
| id | doaj-art-737bae5df8ac4c6eaac850c2a80cc569 |
| institution | Kabale University |
| issn | 0032-5791 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
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| series | Poultry Science |
| spelling | doaj-art-737bae5df8ac4c6eaac850c2a80cc5692025-01-22T05:40:49ZengElsevierPoultry Science0032-57912025-01-011041104646Genomic and virulent characterization of a duck-associated Salmonella serovar Potsdam from ChinaHongli An0Xiamei Kang1Chenhu Huang2Chenghao Jia3Jiaqi Chen4Yingying Huang5Qianzhe Cao6Yan Li7Biao Tang8Min Yue9Department of Veterinary Medicine, Zhejiang University College of Animal Sciences, Hangzhou 310058, China; Hainan Institute of Zhejiang University, Sanya 572025, ChinaDepartment of Veterinary Medicine, Zhejiang University College of Animal Sciences, Hangzhou 310058, ChinaDepartment of Veterinary Medicine, Zhejiang University College of Animal Sciences, Hangzhou 310058, China; Hainan Institute of Zhejiang University, Sanya 572025, ChinaDepartment of Veterinary Medicine, Zhejiang University College of Animal Sciences, Hangzhou 310058, ChinaDepartment of Veterinary Medicine, Zhejiang University College of Animal Sciences, Hangzhou 310058, ChinaDepartment of Veterinary Medicine, Zhejiang University College of Animal Sciences, Hangzhou 310058, China; Hainan Institute of Zhejiang University, Sanya 572025, ChinaDepartment of Veterinary Medicine, Zhejiang University College of Animal Sciences, Hangzhou 310058, ChinaDepartment of Veterinary Medicine, Zhejiang University College of Animal Sciences, Hangzhou 310058, China; Hainan Institute of Zhejiang University, Sanya 572025, ChinaKey Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, ChinaDepartment of Veterinary Medicine, Zhejiang University College of Animal Sciences, Hangzhou 310058, China; Hainan Institute of Zhejiang University, Sanya 572025, China; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 31003, China; Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China; Corresponding author.Salmonella, a common zoonotic pathogen, is a significant concern for public health, particularly when it contaminates animal-borne products. The potential for Salmonella to infect duck embryos and disrupt their normal development not only causes substantial economic losses for the industry but also poses a severe threat to public health. However, there is a lack of understanding about the prevalence of Salmonella in duck embryos and their potential public health implications. Our study aims to fill this gap by providing genomic features of the antimicrobial resistance and virulence potential of Salmonella isolates from dead duck embryos using whole-genome sequencing and in silico toolkits. We also sought to assess the virulent characterization of the major serovar isolates by experimental infection of chicken and duck embryos. Our investigation of 195 duck embryo eggs led to the isolation of 40 (20.51%) Salmonella strains, with Salmonella serovar Potsdam being the most prevalent serovar. Most isolates were resistant to streptomycin (57.3%) and nalidixic acid (50%). Notably, our findings demonstrated that S. Potsdam exhibited a preference for ducks over chickens, suggesting potential host specificity. Additionally, global phylogenomic analysis, incorporating 180 global genomes, revealed a predominant association of S. Potsdam with ducks, supporting an adaptive process specific to the waterfowl. This study determined Salmonella serovars and antimicrobial resistance profiles in dead duck embryos, revealing a rare Salmonella serovar Potsdam with a potential for duck adaption.http://www.sciencedirect.com/science/article/pii/S0032579124012240SalmonellaDuckVirulencePotsdamSerovarHost adaptation |
| spellingShingle | Hongli An Xiamei Kang Chenhu Huang Chenghao Jia Jiaqi Chen Yingying Huang Qianzhe Cao Yan Li Biao Tang Min Yue Genomic and virulent characterization of a duck-associated Salmonella serovar Potsdam from China Poultry Science Salmonella Duck Virulence Potsdam Serovar Host adaptation |
| title | Genomic and virulent characterization of a duck-associated Salmonella serovar Potsdam from China |
| title_full | Genomic and virulent characterization of a duck-associated Salmonella serovar Potsdam from China |
| title_fullStr | Genomic and virulent characterization of a duck-associated Salmonella serovar Potsdam from China |
| title_full_unstemmed | Genomic and virulent characterization of a duck-associated Salmonella serovar Potsdam from China |
| title_short | Genomic and virulent characterization of a duck-associated Salmonella serovar Potsdam from China |
| title_sort | genomic and virulent characterization of a duck associated salmonella serovar potsdam from china |
| topic | Salmonella Duck Virulence Potsdam Serovar Host adaptation |
| url | http://www.sciencedirect.com/science/article/pii/S0032579124012240 |
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