Psudoxanthoma elasticum: An Unusual Case of Gastrointestinal Bleeding

Pseudoxanchoma elasticum (PXE) is an inherited disorder of connective tissue, characterized by calcification and degeneration of elastin. Clinical manifestations of PXE are protean, with skin, eyes and arteries being most commonly involved. Although often a benign condition, gastrointestinal hemorrh...

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Main Authors: Deborah J. Cook, Samih S. Salama, Robert J. Tuttle
Format: Article
Language:English
Published: Wiley 1989-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/1989/974847
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author Deborah J. Cook
Samih S. Salama
Robert J. Tuttle
author_facet Deborah J. Cook
Samih S. Salama
Robert J. Tuttle
author_sort Deborah J. Cook
collection DOAJ
description Pseudoxanchoma elasticum (PXE) is an inherited disorder of connective tissue, characterized by calcification and degeneration of elastin. Clinical manifestations of PXE are protean, with skin, eyes and arteries being most commonly involved. Although often a benign condition, gastrointestinal hemorrhage is a potentially fatal complication. An unusual case of gastrointestinal hemorrhage in a patient with PXE is described and the pathophysiology, clinical presentation and complications of this rare condition are reviewed.
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institution Kabale University
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series Canadian Journal of Gastroenterology
spelling doaj-art-732cb47b224343cdbbd021f528a59d582025-02-03T06:00:47ZengWileyCanadian Journal of Gastroenterology0835-79001989-01-013414114410.1155/1989/974847Psudoxanthoma elasticum: An Unusual Case of Gastrointestinal BleedingDeborah J. Cook0Samih S. Salama1Robert J. Tuttle2Departments of Medicine, Pathology and Radiology, St Joseph’s Hospital, McMaster University, Hamilton, Ontario, CanadaDepartments of Medicine, Pathology and Radiology, St Joseph’s Hospital, McMaster University, Hamilton, Ontario, CanadaDepartments of Medicine, Pathology and Radiology, St Joseph’s Hospital, McMaster University, Hamilton, Ontario, CanadaPseudoxanchoma elasticum (PXE) is an inherited disorder of connective tissue, characterized by calcification and degeneration of elastin. Clinical manifestations of PXE are protean, with skin, eyes and arteries being most commonly involved. Although often a benign condition, gastrointestinal hemorrhage is a potentially fatal complication. An unusual case of gastrointestinal hemorrhage in a patient with PXE is described and the pathophysiology, clinical presentation and complications of this rare condition are reviewed.http://dx.doi.org/10.1155/1989/974847
spellingShingle Deborah J. Cook
Samih S. Salama
Robert J. Tuttle
Psudoxanthoma elasticum: An Unusual Case of Gastrointestinal Bleeding
Canadian Journal of Gastroenterology
title Psudoxanthoma elasticum: An Unusual Case of Gastrointestinal Bleeding
title_full Psudoxanthoma elasticum: An Unusual Case of Gastrointestinal Bleeding
title_fullStr Psudoxanthoma elasticum: An Unusual Case of Gastrointestinal Bleeding
title_full_unstemmed Psudoxanthoma elasticum: An Unusual Case of Gastrointestinal Bleeding
title_short Psudoxanthoma elasticum: An Unusual Case of Gastrointestinal Bleeding
title_sort psudoxanthoma elasticum an unusual case of gastrointestinal bleeding
url http://dx.doi.org/10.1155/1989/974847
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AT samihssalama psudoxanthomaelasticumanunusualcaseofgastrointestinalbleeding
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