Bifurcation in the healing or fibrotic response in a network model of fibrosis: role of the initial injury structure
IntroductionPulmonary fibrosis (PF) is a heterogeneous progressive lung disease characterized by excessive extracellular matrix (ECM) deposition and cross-linking, leading to irreversible tissue stiffening and loss of function. Previous evidence suggests that percolation behavior, where increasing l...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-07-01
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| Series: | Frontiers in Network Physiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnetp.2025.1589216/full |
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