PMAIP1 regulates the progression of follicular thyroid carcinoma through the Wnt3/FOSL1 pathway

PMAIP1 regulates the progression of follicular thyroid carcinoma through the Wnt3/FOSL1 pathway

IntroductionIn thyroid carcinoma (TC), follicular thyroid carcinoma (FTC) represents the second most prevalent pathological type following papillary thyroid carcinoma. Notably, FTC exhibits a more aggressive clinical course and a higher propensity for distant metastasis. However, the underlying mech...

Full description

Saved in:

Bibliographic Details
Main Authors:	Haobo Wang, Fangjian Shang, Yifang Wang, Bo Pang, Longfei Kang, Chuanmin Zhou, Dongyun Li, Zhongxin Li, Xia Jiang, Bo Liu, Zengren Zhao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Oncology
Subjects:	follicular thyroid carcinoma PMAIP1 Wnt3 FOSL1 progression
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1502391/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

FOSL2 activates TGF‐β1‐mediated GLUT1/mTOR signaling to promote diabetic kidney disease
by: Xuelin He, et al.
Published: (2025-02-01)

PMAIP1-mediated glucose metabolism and its impact on the tumor microenvironment in breast cancer: Integration of multi-omics analysis and experimental validation
by: Yidong Zhang, et al.
Published: (2025-02-01)

Research progress of GLP-1RAs in the treatment of type 2 diabetes mellitus
by: Xu He, et al.
Published: (2025-01-01)

Caerin 1.1/1.9-mediated antitumor immunity depends on IFNAR-Stat1 signalling of tumour infiltrating macrophage by autocrine IFNα and is enhanced by CD47 blockade
by: Junjie Li, et al.
Published: (2025-01-01)

ENO1 promotes PDAC progression by inhibiting CD8+ T cell infiltration through upregulating PD-L1 expression via HIF-1α signaling
by: Aziguli Tulamaiti, et al.
Published: (2025-02-01)

Formin protein DAAM1 positively regulates PD-L1 expression via mediating the JAK1/STAT1 axis in pancreatic cancer
by: Rui Xu, et al.
Published: (2025-01-01)

AKT1-Mediated NOTCH1 phosphorylation promotes gastric cancer progression via targeted regulation of IRS-1 transcription
by: Lingshan Zhou, et al.
Published: (2024-12-01)

AdipoR1 enhances the radiation resistance via ESR1/CCNB1IP1/cyclin B1 pathway in hepatocellular carcinoma cells
by: Yuhan Gan, et al.
Published: (2025-01-01)

Proximity extension assay revealed novel inflammatory biomarkers for follicular development and ovarian function: a prospective controlled study combining serum and follicular fluid
by: Chong Wang, et al.
Published: (2025-02-01)

The impact of SLCO1B1 polymorphisms on homocysteine concentrations: evidence for a stronger association in men
by: Xinyuan Hu, et al.
Published: (2025-01-01)

1-Methylcyclopropene Delays Browning and Maintains Aroma in Fresh-Cut Nectarines
by: Rui Zhang, et al.
Published: (2025-01-01)

Fructose 1,6-bisphosphatase 1 is a potential biomarker affecting the malignant phenotype and aerobic glycolysis in glioblastoma
by: Weihong Lu, et al.
Published: (2025-01-01)

Enhanced Oxidative Phosphorylation Driven by TACO1 Mitochondrial Translocation Promotes Stemness and Cisplatin Resistance in Bladder Cancer
by: Minhua Deng, et al.
Published: (2025-02-01)

Virtual biopsy for non-invasive identification of follicular lymphoma histologic transformation using radiomics-based imaging biomarker from PET/CT
by: Chong Jiang, et al.
Published: (2025-01-01)

Ionizing radiation-induced disruption of Rela-Bclaf1-spliceosome regulatory axis in primary spermatocytes causing spermatogenesis dysfunction
by: Hongjian Zhou, et al.
Published: (2025-01-01)

Phosphatidylinositol promoted the proliferation and invasion of pituitary adenoma cells by regulating POU1F1 expression
by: Tongjiang Xu, et al.
Published: (2025-01-01)

SPC25 upregulates CCND1 to promote the progression of esophageal squamous cell carcinoma by inhibiting MDM2-mediated E2F1 ubiquitination
by: Haoyao Jiang, et al.
Published: (2025-03-01)

A Spatio-Temporal Deep Learning Model for Automatic Arctic Sea Ice Classification with Sentinel-1 SAR Imagery
by: Li Zhao, et al.
Published: (2025-01-01)

CircXYLT1 suppresses oxidative stress and promotes vascular remodeling in aging mice carotid artery injury model of atherosclerosis via PTBP1
by: Gang Li, et al.
Published: (2025-03-01)

Design, synthesis, and anti-inflammatory activity of 2H-1,4-benzoxazin-3(4H)-one derivatives modified with 1,2,3-triazole in LPS-induced BV-2 cells
by: Xixi Hou, et al.
Published: (2025-01-01)

Hypofractionated radiotherapy combined with a PD-1 inhibitor, granulocyte macrophage-colony stimulating factor, and thymosin-α1 in advanced metastatic solid tumors: a multicenter Phase II clinical trial
by: Jiamin Yu, et al.
Published: (2025-02-01)

Faith, hope and love - a missionary perspective on three seminal motifs in 1 Thessalonians 1:3
by: P. G. R. de Villiers
Published: (2003-06-01)

Baseline [18F]FDG PET/CT radiomics for predicting interim efficacy in follicular lymphoma treated with first-line R-CHOP
by: Zeying Wen, et al.
Published: (2025-01-01)

Myofibrillogenesis Regulator-1 in Smooth Muscle Cells Modulates Inflammation Signaling Pathways via Regulating ROCK1 Ubiquitination and Degradation to Impact Aortic Dissection
by: Yin H, et al.
Published: (2025-02-01)

Diagnostic utility of LEF1 and β-catenin in WNT pathway tumors with CTNNB1 mutation
by: Can Li, et al.
Published: (2025-01-01)

IDENTIFICATION OF A (1B)1R SUBSTITUTION AND 1BL.1RS TRANSLOCATION IN WINTER WHEAT INTROGRESSION LINES BY CYTOGENETIC AND MOLECULAR METHODS
by: I. I. Motsnyy, et al.
Published: (2014-12-01)

Cuba vs H1N1 Influenza
by: Gail Reed
Published: (2011-04-01)

Screening of West Siberian patients with primary congenital glaucoma for CYP1B1 gene mutations
by: D. E. Ivanoshchuk, et al.
Published: (2020-12-01)

CAR-T CELL THERAPY FOR FOLLICULAR LYMPHOMAS
by: Ugo Testa, et al.
Published: (2024-01-01)

Study on the value of gastrin 17 and aldehyde dehydrogenase 1 in gastric juice for early diagnosis in gastric cancer
by: Yanfang Wang, et al.
Published: (2025-01-01)

Resveratrol contributes to NK cell-mediated breast cancer cytotoxicity by upregulating ULBP2 through miR-17-5p downmodulation and activation of MINK1/JNK/c-Jun signaling
by: Bisha Ding, et al.
Published: (2025-02-01)

Localization and expression of C1QTNF6 in chicken follicles and its regulatory effect on follicular granulosa cells
by: Chong Li, et al.
Published: (2025-01-01)

Mitophagy mediated by HIF-1α/FUNDC1 signaling in tubular cells protects against renal ischemia/reperfusion injury
by: Wenjun Zhang, et al.
Published: (2024-12-01)

Associations of the levels of adipokines and cytokines in individual follicles with in vitro fertilization outcomes in women with different ovarian reserves
by: Xuelan Li, et al.
Published: (2025-01-01)

Exosome‐derived long non‐coding RNA AC010789.1 modified by FTO and hnRNPA2B1 accelerates growth of hair follicle stem cells against androgen alopecia by activating S100A8/Wnt/β‐catenin signalling
by: Shaojun Chu, et al.
Published: (2025-01-01)

Nicotine promotes M2 macrophage polarization through α5-nAChR/SOX2/CSF-1 axis in lung adenocarcinoma
by: Guiyu Kang, et al.
Published: (2024-11-01)

Ginsenoside F1 administration promotes UCP1-dependent fat browning and ameliorates obesity-associated insulin resistance
by: Yuhan Meng, et al.
Published: (2023-11-01)

The sphingosine‐1‐phosphate signaling pathway (sphingosine‐1‐phosphate and its receptor, sphingosine kinase) and epilepsy
by: Lin Wang, et al.
Published: (2025-02-01)

The influence of follicular fluid on the regulation of apoptosis and related genes during IVM of camel oocytes
by: A.A. Ammari, et al.
Published: (2025-01-01)

Computational design of drug candidates for influenza A virus subtype H1N1 by inhibiting the viral neuraminidase-1 enzyme
by: Tambunan Usman Sumo Friend, et al.
Published: (2014-06-01)