The Utility of Thiopurine Methyltransferase Enzyme Testing in Inflammatory Bowel Disease
OBJECTIVE: To assess the levels of red blood cell thiopurine methyltransferase (TPMT) in subjects with inflammatory bowel disease (IBD) and to determine how these levels impacted thiopurine dosing and leukopenia over the first six months of therapy.
Saved in:
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2013-01-01
|
Series: | Canadian Journal of Gastroenterology |
Online Access: | http://dx.doi.org/10.1155/2013/280860 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
_version_ | 1832552781688340480 |
---|---|
author | Laura Chisick Curtis Oleschuk Charles N Bernstein |
author_facet | Laura Chisick Curtis Oleschuk Charles N Bernstein |
author_sort | Laura Chisick |
collection | DOAJ |
description | OBJECTIVE: To assess the levels of red blood cell thiopurine methyltransferase (TPMT) in subjects with inflammatory bowel disease (IBD) and to determine how these levels impacted thiopurine dosing and leukopenia over the first six months of therapy. |
format | Article |
id | doaj-art-7309a79c9ade4464a8aa26ade8d30d49 |
institution | Kabale University |
issn | 0835-7900 |
language | English |
publishDate | 2013-01-01 |
publisher | Wiley |
record_format | Article |
series | Canadian Journal of Gastroenterology |
spelling | doaj-art-7309a79c9ade4464a8aa26ade8d30d492025-02-03T05:57:47ZengWileyCanadian Journal of Gastroenterology0835-79002013-01-01271394310.1155/2013/280860The Utility of Thiopurine Methyltransferase Enzyme Testing in Inflammatory Bowel DiseaseLaura Chisick0Curtis Oleschuk1Charles N Bernstein2Department of Internal Medicine, University of Manitoba IBD Clinical and Research Centre, CanadaDepartment of Pediatrics and Child Health, University of Manitoba, Winnipeg, Manitoba, CanadaDepartment of Internal Medicine, University of Manitoba IBD Clinical and Research Centre, CanadaOBJECTIVE: To assess the levels of red blood cell thiopurine methyltransferase (TPMT) in subjects with inflammatory bowel disease (IBD) and to determine how these levels impacted thiopurine dosing and leukopenia over the first six months of therapy.http://dx.doi.org/10.1155/2013/280860 |
spellingShingle | Laura Chisick Curtis Oleschuk Charles N Bernstein The Utility of Thiopurine Methyltransferase Enzyme Testing in Inflammatory Bowel Disease Canadian Journal of Gastroenterology |
title | The Utility of Thiopurine Methyltransferase Enzyme Testing in Inflammatory Bowel Disease |
title_full | The Utility of Thiopurine Methyltransferase Enzyme Testing in Inflammatory Bowel Disease |
title_fullStr | The Utility of Thiopurine Methyltransferase Enzyme Testing in Inflammatory Bowel Disease |
title_full_unstemmed | The Utility of Thiopurine Methyltransferase Enzyme Testing in Inflammatory Bowel Disease |
title_short | The Utility of Thiopurine Methyltransferase Enzyme Testing in Inflammatory Bowel Disease |
title_sort | utility of thiopurine methyltransferase enzyme testing in inflammatory bowel disease |
url | http://dx.doi.org/10.1155/2013/280860 |
work_keys_str_mv | AT laurachisick theutilityofthiopurinemethyltransferaseenzymetestingininflammatoryboweldisease AT curtisoleschuk theutilityofthiopurinemethyltransferaseenzymetestingininflammatoryboweldisease AT charlesnbernstein theutilityofthiopurinemethyltransferaseenzymetestingininflammatoryboweldisease AT laurachisick utilityofthiopurinemethyltransferaseenzymetestingininflammatoryboweldisease AT curtisoleschuk utilityofthiopurinemethyltransferaseenzymetestingininflammatoryboweldisease AT charlesnbernstein utilityofthiopurinemethyltransferaseenzymetestingininflammatoryboweldisease |