The Utility of Thiopurine Methyltransferase Enzyme Testing in Inflammatory Bowel Disease

OBJECTIVE: To assess the levels of red blood cell thiopurine methyltransferase (TPMT) in subjects with inflammatory bowel disease (IBD) and to determine how these levels impacted thiopurine dosing and leukopenia over the first six months of therapy.

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Bibliographic Details
Main Authors: Laura Chisick, Curtis Oleschuk, Charles N Bernstein
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2013/280860
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author Laura Chisick
Curtis Oleschuk
Charles N Bernstein
author_facet Laura Chisick
Curtis Oleschuk
Charles N Bernstein
author_sort Laura Chisick
collection DOAJ
description OBJECTIVE: To assess the levels of red blood cell thiopurine methyltransferase (TPMT) in subjects with inflammatory bowel disease (IBD) and to determine how these levels impacted thiopurine dosing and leukopenia over the first six months of therapy.
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institution Kabale University
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series Canadian Journal of Gastroenterology
spelling doaj-art-7309a79c9ade4464a8aa26ade8d30d492025-02-03T05:57:47ZengWileyCanadian Journal of Gastroenterology0835-79002013-01-01271394310.1155/2013/280860The Utility of Thiopurine Methyltransferase Enzyme Testing in Inflammatory Bowel DiseaseLaura Chisick0Curtis Oleschuk1Charles N Bernstein2Department of Internal Medicine, University of Manitoba IBD Clinical and Research Centre, CanadaDepartment of Pediatrics and Child Health, University of Manitoba, Winnipeg, Manitoba, CanadaDepartment of Internal Medicine, University of Manitoba IBD Clinical and Research Centre, CanadaOBJECTIVE: To assess the levels of red blood cell thiopurine methyltransferase (TPMT) in subjects with inflammatory bowel disease (IBD) and to determine how these levels impacted thiopurine dosing and leukopenia over the first six months of therapy.http://dx.doi.org/10.1155/2013/280860
spellingShingle Laura Chisick
Curtis Oleschuk
Charles N Bernstein
The Utility of Thiopurine Methyltransferase Enzyme Testing in Inflammatory Bowel Disease
Canadian Journal of Gastroenterology
title The Utility of Thiopurine Methyltransferase Enzyme Testing in Inflammatory Bowel Disease
title_full The Utility of Thiopurine Methyltransferase Enzyme Testing in Inflammatory Bowel Disease
title_fullStr The Utility of Thiopurine Methyltransferase Enzyme Testing in Inflammatory Bowel Disease
title_full_unstemmed The Utility of Thiopurine Methyltransferase Enzyme Testing in Inflammatory Bowel Disease
title_short The Utility of Thiopurine Methyltransferase Enzyme Testing in Inflammatory Bowel Disease
title_sort utility of thiopurine methyltransferase enzyme testing in inflammatory bowel disease
url http://dx.doi.org/10.1155/2013/280860
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