Prevalence of Emergence Delirium and Associated Factors among Older Patients Who Underwent Elective Surgery: A Multicenter Observational Study

Background. Emergence delirium is a common and serious postoperative complication in older surgical patients. It occurs at any time in the perioperative period, during or immediately following emergence from general anesthesia. Unfortunately, it is highly associated with postoperative complications...

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Main Authors: Gezahegn Tesfaye Mekonin, Megersa Kelbesa Olika, Mitiku Birhanu Wedajo, Ashanafi Tolasa Badada, Abebe Dukessa Dubiwak, Tajera Tageza Ilala, Mamo Nigatu Gebre
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Anesthesiology Research and Practice
Online Access:http://dx.doi.org/10.1155/2022/2711310
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author Gezahegn Tesfaye Mekonin
Megersa Kelbesa Olika
Mitiku Birhanu Wedajo
Ashanafi Tolasa Badada
Abebe Dukessa Dubiwak
Tajera Tageza Ilala
Mamo Nigatu Gebre
author_facet Gezahegn Tesfaye Mekonin
Megersa Kelbesa Olika
Mitiku Birhanu Wedajo
Ashanafi Tolasa Badada
Abebe Dukessa Dubiwak
Tajera Tageza Ilala
Mamo Nigatu Gebre
author_sort Gezahegn Tesfaye Mekonin
collection DOAJ
description Background. Emergence delirium is a common and serious postoperative complication in older surgical patients. It occurs at any time in the perioperative period, during or immediately following emergence from general anesthesia. Unfortunately, it is highly associated with postoperative complications such as a decrease in functional capacity, prolonged hospital stay, an increase in health care costs, and morbidity and mortality. The goal of this study was to determine the prevalence of emergence delirium and associated factors among older patients who underwent elective surgery in the teaching hospitals of Ethiopia at the postanesthesia care unit in 2021. Methods. A multicenter prospective observational study was conducted at the postanesthetic care unit in the four teaching hospitals of Ethiopia. Older surgical patients admitted to the postanesthesia care unit who underwent elective surgery in the four teaching hospitals of Ethiopia were selected by using simple random sampling. Pretested structured questionnaire was used to collect data. Data were entered into EpiData (version 4.6) and exported to the SPSS (version 25.0). Binary logistic regression was used to identify factors independently associated with the emergence delirium. Results. Out of 384 older patients included in the study, the prevalence of emergence delirium was 27.6%. Preoperative low hemoglobin levels (AOR: 2.0, 95% CI; 1.77–3.46), opioid (AOR: 8.0, 95% CI; 3.22–27.8), anticholinergic premedications (AOR: 8.5, 95% CI; 6.85–17.35), and postoperative pain (AOR: 3.10, 95 CI; 2.07–9.84) at PACU were independently associated with emergence delirium. Conclusion. The prevalence of emergence delirium was high among older patients who underwent elective surgery. Opioid and anticholinergic premedication, low preoperative hemoglobin, and the presence of postoperative pain were independently associated with the emergence delirium. Adequate preoperative optimization and postoperative analgesia may reduce the prevalence of emergence delirium.
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spelling doaj-art-730764fcb35c47bf9be06e35506b20142025-02-03T05:49:20ZengWileyAnesthesiology Research and Practice1687-69702022-01-01202210.1155/2022/2711310Prevalence of Emergence Delirium and Associated Factors among Older Patients Who Underwent Elective Surgery: A Multicenter Observational StudyGezahegn Tesfaye Mekonin0Megersa Kelbesa Olika1Mitiku Birhanu Wedajo2Ashanafi Tolasa Badada3Abebe Dukessa Dubiwak4Tajera Tageza Ilala5Mamo Nigatu Gebre6Department of AnesthesiaDepartment of AnesthesiaDepartment of AnesthesiaDepartment of AnesthesiaDepartment of Biomedical ScienceDepartment of AnesthesiaDepartment of EpidemiologyBackground. Emergence delirium is a common and serious postoperative complication in older surgical patients. It occurs at any time in the perioperative period, during or immediately following emergence from general anesthesia. Unfortunately, it is highly associated with postoperative complications such as a decrease in functional capacity, prolonged hospital stay, an increase in health care costs, and morbidity and mortality. The goal of this study was to determine the prevalence of emergence delirium and associated factors among older patients who underwent elective surgery in the teaching hospitals of Ethiopia at the postanesthesia care unit in 2021. Methods. A multicenter prospective observational study was conducted at the postanesthetic care unit in the four teaching hospitals of Ethiopia. Older surgical patients admitted to the postanesthesia care unit who underwent elective surgery in the four teaching hospitals of Ethiopia were selected by using simple random sampling. Pretested structured questionnaire was used to collect data. Data were entered into EpiData (version 4.6) and exported to the SPSS (version 25.0). Binary logistic regression was used to identify factors independently associated with the emergence delirium. Results. Out of 384 older patients included in the study, the prevalence of emergence delirium was 27.6%. Preoperative low hemoglobin levels (AOR: 2.0, 95% CI; 1.77–3.46), opioid (AOR: 8.0, 95% CI; 3.22–27.8), anticholinergic premedications (AOR: 8.5, 95% CI; 6.85–17.35), and postoperative pain (AOR: 3.10, 95 CI; 2.07–9.84) at PACU were independently associated with emergence delirium. Conclusion. The prevalence of emergence delirium was high among older patients who underwent elective surgery. Opioid and anticholinergic premedication, low preoperative hemoglobin, and the presence of postoperative pain were independently associated with the emergence delirium. Adequate preoperative optimization and postoperative analgesia may reduce the prevalence of emergence delirium.http://dx.doi.org/10.1155/2022/2711310
spellingShingle Gezahegn Tesfaye Mekonin
Megersa Kelbesa Olika
Mitiku Birhanu Wedajo
Ashanafi Tolasa Badada
Abebe Dukessa Dubiwak
Tajera Tageza Ilala
Mamo Nigatu Gebre
Prevalence of Emergence Delirium and Associated Factors among Older Patients Who Underwent Elective Surgery: A Multicenter Observational Study
Anesthesiology Research and Practice
title Prevalence of Emergence Delirium and Associated Factors among Older Patients Who Underwent Elective Surgery: A Multicenter Observational Study
title_full Prevalence of Emergence Delirium and Associated Factors among Older Patients Who Underwent Elective Surgery: A Multicenter Observational Study
title_fullStr Prevalence of Emergence Delirium and Associated Factors among Older Patients Who Underwent Elective Surgery: A Multicenter Observational Study
title_full_unstemmed Prevalence of Emergence Delirium and Associated Factors among Older Patients Who Underwent Elective Surgery: A Multicenter Observational Study
title_short Prevalence of Emergence Delirium and Associated Factors among Older Patients Who Underwent Elective Surgery: A Multicenter Observational Study
title_sort prevalence of emergence delirium and associated factors among older patients who underwent elective surgery a multicenter observational study
url http://dx.doi.org/10.1155/2022/2711310
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