Spontaneous Yersinia enterocolitica Septicemia in a Patient with Iron Overload
Yersinia enterocolitica septicemia is described in a patient with transfusional iron overload and a myelodysplastic syndrome. The organism was biotype 1 serotype 0:5,27 and carried a virulence-encoding plasmid. It was calcium-dependent, autoagglutinating and virulent to orally challenged mice, but n...
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Format: | Article |
Language: | English |
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Wiley
1990-01-01
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Series: | Canadian Journal of Infectious Diseases |
Online Access: | http://dx.doi.org/10.1155/1990/671489 |
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author | Steven S Larigakis Michael A Noble Terence G Sparling |
author_facet | Steven S Larigakis Michael A Noble Terence G Sparling |
author_sort | Steven S Larigakis |
collection | DOAJ |
description | Yersinia enterocolitica septicemia is described in a patient with transfusional iron overload and a myelodysplastic syndrome. The organism was biotype 1 serotype 0:5,27 and carried a virulence-encoding plasmid. It was calcium-dependent, autoagglutinating and virulent to orally challenged mice, but not resistant to the bacteriocidal activity of serum. The patient had depressed neutrophil chemotaxis and bactericidal activity. In this case, both host and microbial factors were present to select out this particular bacteremic disease. Patients with iron overload states should be recognized as compromised hosts and potentially susceptible to spontaneous sepsis due to Y enterocolitica. |
format | Article |
id | doaj-art-72cc7d38f8d64208b66589a63edbd10d |
institution | Kabale University |
issn | 1180-2332 |
language | English |
publishDate | 1990-01-01 |
publisher | Wiley |
record_format | Article |
series | Canadian Journal of Infectious Diseases |
spelling | doaj-art-72cc7d38f8d64208b66589a63edbd10d2025-02-03T01:21:00ZengWileyCanadian Journal of Infectious Diseases1180-23321990-01-0112576010.1155/1990/671489Spontaneous Yersinia enterocolitica Septicemia in a Patient with Iron OverloadSteven S Larigakis0Michael A Noble1Terence G Sparling2University Hospital and the University of British Columbia, Vancouver, British Columbia, CanadaUniversity Hospital and the University of British Columbia, Vancouver, British Columbia, CanadaUniversity Hospital and the University of British Columbia, Vancouver, British Columbia, CanadaYersinia enterocolitica septicemia is described in a patient with transfusional iron overload and a myelodysplastic syndrome. The organism was biotype 1 serotype 0:5,27 and carried a virulence-encoding plasmid. It was calcium-dependent, autoagglutinating and virulent to orally challenged mice, but not resistant to the bacteriocidal activity of serum. The patient had depressed neutrophil chemotaxis and bactericidal activity. In this case, both host and microbial factors were present to select out this particular bacteremic disease. Patients with iron overload states should be recognized as compromised hosts and potentially susceptible to spontaneous sepsis due to Y enterocolitica.http://dx.doi.org/10.1155/1990/671489 |
spellingShingle | Steven S Larigakis Michael A Noble Terence G Sparling Spontaneous Yersinia enterocolitica Septicemia in a Patient with Iron Overload Canadian Journal of Infectious Diseases |
title | Spontaneous Yersinia enterocolitica Septicemia in a Patient with Iron Overload |
title_full | Spontaneous Yersinia enterocolitica Septicemia in a Patient with Iron Overload |
title_fullStr | Spontaneous Yersinia enterocolitica Septicemia in a Patient with Iron Overload |
title_full_unstemmed | Spontaneous Yersinia enterocolitica Septicemia in a Patient with Iron Overload |
title_short | Spontaneous Yersinia enterocolitica Septicemia in a Patient with Iron Overload |
title_sort | spontaneous yersinia enterocolitica septicemia in a patient with iron overload |
url | http://dx.doi.org/10.1155/1990/671489 |
work_keys_str_mv | AT stevenslarigakis spontaneousyersiniaenterocoliticasepticemiainapatientwithironoverload AT michaelanoble spontaneousyersiniaenterocoliticasepticemiainapatientwithironoverload AT terencegsparling spontaneousyersiniaenterocoliticasepticemiainapatientwithironoverload |