Spontaneous Yersinia enterocolitica Septicemia in a Patient with Iron Overload

Yersinia enterocolitica septicemia is described in a patient with transfusional iron overload and a myelodysplastic syndrome. The organism was biotype 1 serotype 0:5,27 and carried a virulence-encoding plasmid. It was calcium-dependent, autoagglutinating and virulent to orally challenged mice, but n...

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Main Authors: Steven S Larigakis, Michael A Noble, Terence G Sparling
Format: Article
Language:English
Published: Wiley 1990-01-01
Series:Canadian Journal of Infectious Diseases
Online Access:http://dx.doi.org/10.1155/1990/671489
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author Steven S Larigakis
Michael A Noble
Terence G Sparling
author_facet Steven S Larigakis
Michael A Noble
Terence G Sparling
author_sort Steven S Larigakis
collection DOAJ
description Yersinia enterocolitica septicemia is described in a patient with transfusional iron overload and a myelodysplastic syndrome. The organism was biotype 1 serotype 0:5,27 and carried a virulence-encoding plasmid. It was calcium-dependent, autoagglutinating and virulent to orally challenged mice, but not resistant to the bacteriocidal activity of serum. The patient had depressed neutrophil chemotaxis and bactericidal activity. In this case, both host and microbial factors were present to select out this particular bacteremic disease. Patients with iron overload states should be recognized as compromised hosts and potentially susceptible to spontaneous sepsis due to Y enterocolitica.
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institution Kabale University
issn 1180-2332
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publishDate 1990-01-01
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series Canadian Journal of Infectious Diseases
spelling doaj-art-72cc7d38f8d64208b66589a63edbd10d2025-02-03T01:21:00ZengWileyCanadian Journal of Infectious Diseases1180-23321990-01-0112576010.1155/1990/671489Spontaneous Yersinia enterocolitica Septicemia in a Patient with Iron OverloadSteven S Larigakis0Michael A Noble1Terence G Sparling2University Hospital and the University of British Columbia, Vancouver, British Columbia, CanadaUniversity Hospital and the University of British Columbia, Vancouver, British Columbia, CanadaUniversity Hospital and the University of British Columbia, Vancouver, British Columbia, CanadaYersinia enterocolitica septicemia is described in a patient with transfusional iron overload and a myelodysplastic syndrome. The organism was biotype 1 serotype 0:5,27 and carried a virulence-encoding plasmid. It was calcium-dependent, autoagglutinating and virulent to orally challenged mice, but not resistant to the bacteriocidal activity of serum. The patient had depressed neutrophil chemotaxis and bactericidal activity. In this case, both host and microbial factors were present to select out this particular bacteremic disease. Patients with iron overload states should be recognized as compromised hosts and potentially susceptible to spontaneous sepsis due to Y enterocolitica.http://dx.doi.org/10.1155/1990/671489
spellingShingle Steven S Larigakis
Michael A Noble
Terence G Sparling
Spontaneous Yersinia enterocolitica Septicemia in a Patient with Iron Overload
Canadian Journal of Infectious Diseases
title Spontaneous Yersinia enterocolitica Septicemia in a Patient with Iron Overload
title_full Spontaneous Yersinia enterocolitica Septicemia in a Patient with Iron Overload
title_fullStr Spontaneous Yersinia enterocolitica Septicemia in a Patient with Iron Overload
title_full_unstemmed Spontaneous Yersinia enterocolitica Septicemia in a Patient with Iron Overload
title_short Spontaneous Yersinia enterocolitica Septicemia in a Patient with Iron Overload
title_sort spontaneous yersinia enterocolitica septicemia in a patient with iron overload
url http://dx.doi.org/10.1155/1990/671489
work_keys_str_mv AT stevenslarigakis spontaneousyersiniaenterocoliticasepticemiainapatientwithironoverload
AT michaelanoble spontaneousyersiniaenterocoliticasepticemiainapatientwithironoverload
AT terencegsparling spontaneousyersiniaenterocoliticasepticemiainapatientwithironoverload