Role of crotoxin, a phospholipase A2 isolated from Crotalus durissus terrificus snake venom, on inflammatory and immune reactions
Background: Crotoxin (CTX) is a potent neurotoxin from Crotalus durissus terrificus snake venom (CdtV) composed of two subunits: one without catalytic activity (crotapotin), and a basic phospolipase A2. Recent data have demonstrated that CdtV or CTX inhibit some immune and inflammatory reactions.
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2001-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1080/09629350124986 |
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| author | Diva F. Cardoso Monica Lopes-Ferreira Eliana L. Faquim-Mauro Mahasti S. Macedo Sandra H. P. Farsky |
| author_facet | Diva F. Cardoso Monica Lopes-Ferreira Eliana L. Faquim-Mauro Mahasti S. Macedo Sandra H. P. Farsky |
| author_sort | Diva F. Cardoso |
| collection | DOAJ |
| description | Background: Crotoxin (CTX) is a potent neurotoxin from
Crotalus durissus terrificus snake venom (CdtV) composed of two subunits: one without catalytic activity (crotapotin), and a basic phospolipase A2. Recent data have demonstrated that CdtV or CTX inhibit some immune and inflammatory reactions. |
| format | Article |
| id | doaj-art-72618d63bbd84999aa1ab70b9ff67773 |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2001-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-72618d63bbd84999aa1ab70b9ff677732025-02-03T05:58:51ZengWileyMediators of Inflammation0962-93511466-18612001-01-0110312513310.1080/09629350124986Role of crotoxin, a phospholipase A2 isolated from Crotalus durissus terrificus snake venom, on inflammatory and immune reactionsDiva F. Cardoso0Monica Lopes-Ferreira1Eliana L. Faquim-Mauro2Mahasti S. Macedo3Sandra H. P. Farsky4Laboratory of Immunopathology, Institute Butantan, Av. Vital Brazil, 1500 São Paulo, São Paulo 05503–900, SP, BrazilLaboratory of Immunopathology, Institute Butantan, Av. Vital Brazil, 1500 São Paulo, São Paulo 05503–900, SP, BrazilDepartment of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, BrazilDepartment of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, BrazilLaboratory of Immunochemistry, Institute Butantan, Av. Vital Brazil, 1500 São Paulo, São Paulo 05503–900, SP, BrazilBackground: Crotoxin (CTX) is a potent neurotoxin from Crotalus durissus terrificus snake venom (CdtV) composed of two subunits: one without catalytic activity (crotapotin), and a basic phospolipase A2. Recent data have demonstrated that CdtV or CTX inhibit some immune and inflammatory reactions.http://dx.doi.org/10.1080/09629350124986 |
| spellingShingle | Diva F. Cardoso Monica Lopes-Ferreira Eliana L. Faquim-Mauro Mahasti S. Macedo Sandra H. P. Farsky Role of crotoxin, a phospholipase A2 isolated from Crotalus durissus terrificus snake venom, on inflammatory and immune reactions Mediators of Inflammation |
| title | Role of crotoxin, a phospholipase A2 isolated from Crotalus durissus terrificus snake venom, on inflammatory and immune reactions |
| title_full | Role of crotoxin, a phospholipase A2 isolated from Crotalus durissus terrificus snake venom, on inflammatory and immune reactions |
| title_fullStr | Role of crotoxin, a phospholipase A2 isolated from Crotalus durissus terrificus snake venom, on inflammatory and immune reactions |
| title_full_unstemmed | Role of crotoxin, a phospholipase A2 isolated from Crotalus durissus terrificus snake venom, on inflammatory and immune reactions |
| title_short | Role of crotoxin, a phospholipase A2 isolated from Crotalus durissus terrificus snake venom, on inflammatory and immune reactions |
| title_sort | role of crotoxin a phospholipase a2 isolated from crotalus durissus terrificus snake venom on inflammatory and immune reactions |
| url | http://dx.doi.org/10.1080/09629350124986 |
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