Painless Livedoid Vasculopathy in a Patient with G20210A Prothrombin Gene Mutation
87 year old Caucasian female with chronic painless non-healing ulcers over malleoli was admitted to the hospital. On a physical examination, there were two bilateral and laterally located malleoli ulcers with no discharge. A thorough work up was done: lower extremities venous and arterial Doppler ul...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/910231 |
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| author | Aibek E. Mirrakhimov Erwin Velasquez Kho Alaa Ali |
| author_facet | Aibek E. Mirrakhimov Erwin Velasquez Kho Alaa Ali |
| author_sort | Aibek E. Mirrakhimov |
| collection | DOAJ |
| description | 87 year old Caucasian female with chronic painless non-healing ulcers over malleoli was admitted to the hospital. On a physical examination, there were two bilateral and laterally located malleoli ulcers with no discharge. A thorough work up was done: lower extremities venous and arterial Doppler ultrasound did not show any evidence of venous and arterial disease respectively. Heterozygous G20210A Prothrombin gene mutation was found, and the patient was started on anticoagulation. This case reports highlights a possibility of a painless livedoid vasculopathy presentation in a patient without significant past thrombotic events. Therefore, it is important to consider livedoid vasculopathy in the differential in a patient with painless ulcerative, atrophic and/or nodular skin lesions over the shins and malleoli. |
| format | Article |
| id | doaj-art-72560bc602304d33a3d37de4a6c3e4e5 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-72560bc602304d33a3d37de4a6c3e4e52025-02-03T06:48:38ZengWileyCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/910231910231Painless Livedoid Vasculopathy in a Patient with G20210A Prothrombin Gene MutationAibek E. Mirrakhimov0Erwin Velasquez Kho1Alaa Ali2Department of Internal Medicine, Saint Joseph Hospital, 2900 N. Lake Shore, Chicago, IL 60657, USADepartment of Internal Medicine, Saint Joseph Hospital, 2900 N. Lake Shore, Chicago, IL 60657, USADepartment of Internal Medicine, Saint Joseph Hospital, 2900 N. Lake Shore, Chicago, IL 60657, USA87 year old Caucasian female with chronic painless non-healing ulcers over malleoli was admitted to the hospital. On a physical examination, there were two bilateral and laterally located malleoli ulcers with no discharge. A thorough work up was done: lower extremities venous and arterial Doppler ultrasound did not show any evidence of venous and arterial disease respectively. Heterozygous G20210A Prothrombin gene mutation was found, and the patient was started on anticoagulation. This case reports highlights a possibility of a painless livedoid vasculopathy presentation in a patient without significant past thrombotic events. Therefore, it is important to consider livedoid vasculopathy in the differential in a patient with painless ulcerative, atrophic and/or nodular skin lesions over the shins and malleoli.http://dx.doi.org/10.1155/2012/910231 |
| spellingShingle | Aibek E. Mirrakhimov Erwin Velasquez Kho Alaa Ali Painless Livedoid Vasculopathy in a Patient with G20210A Prothrombin Gene Mutation Case Reports in Medicine |
| title | Painless Livedoid Vasculopathy in a Patient with G20210A Prothrombin Gene Mutation |
| title_full | Painless Livedoid Vasculopathy in a Patient with G20210A Prothrombin Gene Mutation |
| title_fullStr | Painless Livedoid Vasculopathy in a Patient with G20210A Prothrombin Gene Mutation |
| title_full_unstemmed | Painless Livedoid Vasculopathy in a Patient with G20210A Prothrombin Gene Mutation |
| title_short | Painless Livedoid Vasculopathy in a Patient with G20210A Prothrombin Gene Mutation |
| title_sort | painless livedoid vasculopathy in a patient with g20210a prothrombin gene mutation |
| url | http://dx.doi.org/10.1155/2012/910231 |
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