Development and validation of headspace gas chromatography with a flame ionization detector method for the determination of ethanol in the vitreous humor

Qualitative and quantitative testing of ethanol in post-mortem samples is an important analytical procedure that provides accurate, precise, and reliable results. Given the complexity of the issue, obtaining a realistic picture of lifelong alcoholemia requires supporting blood ethanol findings with...

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Main Authors: Mihajlović Filip, Andrić Ivana, Slović Živana, Vujović Maja, Piskulić Kristina, Đorđević Snežana
Format: Article
Language:English
Published: De Gruyter 2025-01-01
Series:Open Medicine
Subjects:
Online Access:https://doi.org/10.1515/med-2024-1123
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author Mihajlović Filip
Andrić Ivana
Slović Živana
Vujović Maja
Piskulić Kristina
Đorđević Snežana
author_facet Mihajlović Filip
Andrić Ivana
Slović Živana
Vujović Maja
Piskulić Kristina
Đorđević Snežana
author_sort Mihajlović Filip
collection DOAJ
description Qualitative and quantitative testing of ethanol in post-mortem samples is an important analytical procedure that provides accurate, precise, and reliable results. Given the complexity of the issue, obtaining a realistic picture of lifelong alcoholemia requires supporting blood ethanol findings with analyses of alternative samples, primarily vitreous humor (VH).
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institution Kabale University
issn 2391-5463
language English
publishDate 2025-01-01
publisher De Gruyter
record_format Article
series Open Medicine
spelling doaj-art-72545a84ceb8483b96050e306f2869f72025-01-20T11:09:04ZengDe GruyterOpen Medicine2391-54632025-01-012011050610.1515/med-2024-1123Development and validation of headspace gas chromatography with a flame ionization detector method for the determination of ethanol in the vitreous humorMihajlović Filip0Andrić Ivana1Slović Živana2Vujović Maja3Piskulić Kristina4Đorđević Snežana5Department of Pharmacology and Toxicology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, 34000, SerbiaDepartment of Forensic Medicine, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, 34000, SerbiaDepartment of Forensic Medicine, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, 34000, SerbiaDepartment of Pharmacy, Faculty of Medicine, University of Nis, Nis, 18000, SerbiaDepartment of Chemistry, Faculty of Science, University of Kragujevac, Radoja Domanovića 12, Kragujevac, 34000, SerbiaDepartment of Toxicological Chemistry, National Poison Control Center, Military Medical Academy, Belgrade, 11000, SerbiaQualitative and quantitative testing of ethanol in post-mortem samples is an important analytical procedure that provides accurate, precise, and reliable results. Given the complexity of the issue, obtaining a realistic picture of lifelong alcoholemia requires supporting blood ethanol findings with analyses of alternative samples, primarily vitreous humor (VH).https://doi.org/10.1515/med-2024-1123alcoholpostmortem analysisalternative samplesinstrumental methods
spellingShingle Mihajlović Filip
Andrić Ivana
Slović Živana
Vujović Maja
Piskulić Kristina
Đorđević Snežana
Development and validation of headspace gas chromatography with a flame ionization detector method for the determination of ethanol in the vitreous humor
Open Medicine
alcohol
postmortem analysis
alternative samples
instrumental methods
title Development and validation of headspace gas chromatography with a flame ionization detector method for the determination of ethanol in the vitreous humor
title_full Development and validation of headspace gas chromatography with a flame ionization detector method for the determination of ethanol in the vitreous humor
title_fullStr Development and validation of headspace gas chromatography with a flame ionization detector method for the determination of ethanol in the vitreous humor
title_full_unstemmed Development and validation of headspace gas chromatography with a flame ionization detector method for the determination of ethanol in the vitreous humor
title_short Development and validation of headspace gas chromatography with a flame ionization detector method for the determination of ethanol in the vitreous humor
title_sort development and validation of headspace gas chromatography with a flame ionization detector method for the determination of ethanol in the vitreous humor
topic alcohol
postmortem analysis
alternative samples
instrumental methods
url https://doi.org/10.1515/med-2024-1123
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