Malignant Biliary Obstruction: Evidence for Best Practice

What should be done next? Is the stricture benign? Is it resectable? Should I place a stent? Which one? These are some of the questions one ponders when dealing with biliary strictures. In resectable cases, ongoing questions remain as to whether the biliary tree should be drained prior to surgery. I...

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Main Authors: Leonardo Zorrón Cheng Tao Pu, Rajvinder Singh, Cheong Kuan Loong, Eduardo Guimarães Hourneaux de Moura
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2016/3296801
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author Leonardo Zorrón Cheng Tao Pu
Rajvinder Singh
Cheong Kuan Loong
Eduardo Guimarães Hourneaux de Moura
author_facet Leonardo Zorrón Cheng Tao Pu
Rajvinder Singh
Cheong Kuan Loong
Eduardo Guimarães Hourneaux de Moura
author_sort Leonardo Zorrón Cheng Tao Pu
collection DOAJ
description What should be done next? Is the stricture benign? Is it resectable? Should I place a stent? Which one? These are some of the questions one ponders when dealing with biliary strictures. In resectable cases, ongoing questions remain as to whether the biliary tree should be drained prior to surgery. In palliative cases, the relief of obstruction remains the main goal. Options for palliative therapy include surgical bypass, percutaneous drainage, and stenting or endoscopic stenting (transpapillary or via an endoscopic ultrasound approach). This review gathers scientific foundations behind these interventions. For operable cases, preoperative biliary drainage should not be performed unless there is evidence of cholangitis, there is delay in surgical intervention, or intense jaundice is present. For inoperable cases, transpapillary stenting after sphincterotomy is preferable over percutaneous drainage. The use of plastic stents (PS) has no benefit over Self-Expandable Metallic Stents (SEMS). In case transpapillary drainage is not possible, Endoscopic Ultrasonography- (EUS-) guided drainage is still an option over percutaneous means. There is no significant difference between the types of SEMS and its indication should be individualized.
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institution Kabale University
issn 1687-6121
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language English
publishDate 2016-01-01
publisher Wiley
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series Gastroenterology Research and Practice
spelling doaj-art-7235b18a71374d388011216b138913872025-02-03T01:26:14ZengWileyGastroenterology Research and Practice1687-61211687-630X2016-01-01201610.1155/2016/32968013296801Malignant Biliary Obstruction: Evidence for Best PracticeLeonardo Zorrón Cheng Tao Pu0Rajvinder Singh1Cheong Kuan Loong2Eduardo Guimarães Hourneaux de Moura3Setor de Endoscopia Gastrointestinal, Departamento de Gastroenterologia, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, 05403-000 São Paulo, SP, BrazilGastroenterology Department, Lyell McEwen Hospital, Adelaide, Haydown Road, Elizabeth Vale, SA 5112, AustraliaGastroenterology Department, Lyell McEwen Hospital, Adelaide, Haydown Road, Elizabeth Vale, SA 5112, AustraliaSetor de Endoscopia Gastrointestinal, Departamento de Gastroenterologia, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, 05403-000 São Paulo, SP, BrazilWhat should be done next? Is the stricture benign? Is it resectable? Should I place a stent? Which one? These are some of the questions one ponders when dealing with biliary strictures. In resectable cases, ongoing questions remain as to whether the biliary tree should be drained prior to surgery. In palliative cases, the relief of obstruction remains the main goal. Options for palliative therapy include surgical bypass, percutaneous drainage, and stenting or endoscopic stenting (transpapillary or via an endoscopic ultrasound approach). This review gathers scientific foundations behind these interventions. For operable cases, preoperative biliary drainage should not be performed unless there is evidence of cholangitis, there is delay in surgical intervention, or intense jaundice is present. For inoperable cases, transpapillary stenting after sphincterotomy is preferable over percutaneous drainage. The use of plastic stents (PS) has no benefit over Self-Expandable Metallic Stents (SEMS). In case transpapillary drainage is not possible, Endoscopic Ultrasonography- (EUS-) guided drainage is still an option over percutaneous means. There is no significant difference between the types of SEMS and its indication should be individualized.http://dx.doi.org/10.1155/2016/3296801
spellingShingle Leonardo Zorrón Cheng Tao Pu
Rajvinder Singh
Cheong Kuan Loong
Eduardo Guimarães Hourneaux de Moura
Malignant Biliary Obstruction: Evidence for Best Practice
Gastroenterology Research and Practice
title Malignant Biliary Obstruction: Evidence for Best Practice
title_full Malignant Biliary Obstruction: Evidence for Best Practice
title_fullStr Malignant Biliary Obstruction: Evidence for Best Practice
title_full_unstemmed Malignant Biliary Obstruction: Evidence for Best Practice
title_short Malignant Biliary Obstruction: Evidence for Best Practice
title_sort malignant biliary obstruction evidence for best practice
url http://dx.doi.org/10.1155/2016/3296801
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AT rajvindersingh malignantbiliaryobstructionevidenceforbestpractice
AT cheongkuanloong malignantbiliaryobstructionevidenceforbestpractice
AT eduardoguimaraeshourneauxdemoura malignantbiliaryobstructionevidenceforbestpractice