Tumor-associated macrophages derived exosomal circPLK1 promotes resistance to EGFR inhibitor osimertinib in non-small cell lung cancer

Abstract Background Circular RNA (circRNA) is involved in the occurrence and development of many cancers. It has been reported that circRNA Polo like kinase 1 (PLK1) is up-regulated in non-small cell lung cancer (NSCLC), but the mechanism of circPLK1 in NSCLC remains to be further explored. Methods...

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Bibliographic Details
Main Authors: Chuankui Li, Xinyu Sun, Zuyi Wang
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-025-03025-w
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