How does chronic pain lead to memory loss?

A dysfunctional signaling pathway in the hippocampus has been linked to chronic pain-related memory impairment in mice.

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Main Authors: Suelen Pereira, Ivan Tomsic, Robson da Costa, Mychael V Lourenco
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-01-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/105633
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author Suelen Pereira
Ivan Tomsic
Robson da Costa
Mychael V Lourenco
author_facet Suelen Pereira
Ivan Tomsic
Robson da Costa
Mychael V Lourenco
author_sort Suelen Pereira
collection DOAJ
description A dysfunctional signaling pathway in the hippocampus has been linked to chronic pain-related memory impairment in mice.
format Article
id doaj-art-7206387b4e2f4de58a1b3fcf4bea3f4e
institution Kabale University
issn 2050-084X
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publishDate 2025-01-01
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spelling doaj-art-7206387b4e2f4de58a1b3fcf4bea3f4e2025-01-27T15:18:36ZengeLife Sciences Publications LtdeLife2050-084X2025-01-011410.7554/eLife.105633How does chronic pain lead to memory loss?Suelen Pereira0Ivan Tomsic1Robson da Costa2https://orcid.org/0000-0002-1675-4742Mychael V Lourenco3https://orcid.org/0000-0002-1078-0296School of Pharmacy, Federal University of Rio de Janeiro, Rio de Janeiro, BrazilInstitute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, BrazilSchool of Pharmacy, Federal University of Rio de Janeiro, Rio de Janeiro, BrazilInstitute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; Department of Biochemistry and Tissue Biology, Institute of Biology, State University of Campinas, Campinas, BrazilA dysfunctional signaling pathway in the hippocampus has been linked to chronic pain-related memory impairment in mice.https://elifesciences.org/articles/105633chronic painmemorydentate gyrussphingosine 1-phosphatesynaptic plasticity
spellingShingle Suelen Pereira
Ivan Tomsic
Robson da Costa
Mychael V Lourenco
How does chronic pain lead to memory loss?
eLife
chronic pain
memory
dentate gyrus
sphingosine 1-phosphate
synaptic plasticity
title How does chronic pain lead to memory loss?
title_full How does chronic pain lead to memory loss?
title_fullStr How does chronic pain lead to memory loss?
title_full_unstemmed How does chronic pain lead to memory loss?
title_short How does chronic pain lead to memory loss?
title_sort how does chronic pain lead to memory loss
topic chronic pain
memory
dentate gyrus
sphingosine 1-phosphate
synaptic plasticity
url https://elifesciences.org/articles/105633
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AT robsondacosta howdoeschronicpainleadtomemoryloss
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