Application of Multidomain Cognitive Training in a Tele-Neurorehabilitation Setting for Treatment of Post-Stroke Cognitive Disorders
Purpose: Cognitive dysfunctions are still very common in the chronic phase of stroke when patients are discharged from neurorehabilitation centers. Even individuals who appear to have made a full clinical recovery may exhibit new deficiencies at home. Here, we present evidence of a novel kind of the...
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2024-12-01
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| Online Access: | https://www.mdpi.com/2076-3425/15/1/11 |
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| author | Marianna Contrada Loris Pignolo Martina Vatrano Caterina Pucci Isabel Mantia Federica Scarfone Maria Quintieri Antonio Cerasa Gennarina Arabia |
| author_facet | Marianna Contrada Loris Pignolo Martina Vatrano Caterina Pucci Isabel Mantia Federica Scarfone Maria Quintieri Antonio Cerasa Gennarina Arabia |
| author_sort | Marianna Contrada |
| collection | DOAJ |
| description | Purpose: Cognitive dysfunctions are still very common in the chronic phase of stroke when patients are discharged from neurorehabilitation centers. Even individuals who appear to have made a full clinical recovery may exhibit new deficiencies at home. Here, we present evidence of a novel kind of therapy at home aimed at contrasting the heterogenic evolution of stroke patients using a multidomain cognitive approach. Methods: Eighteen ischemic stroke patients were assessed in a within-subject longitudinal design (age 62.33 ± 11.1 years; eight men). Patients underwent the Tele-NeuroRehabilitation (TNR) multidomain cognitive training treatment using the Virtual Reality Rehabilitation System (VRRS) five times a week for 1 h sessions for four consecutive weeks. The protocol included the stimulation of specific cognitive functions, such as logical skills, praxis skills, attention, executive functions, memory, space time orientation and perception, and speech therapy. To determine neuropsychological changes, patients were evaluated before the sessions (T0), at the end of the sessions (T1), and after six months (T2). Results: The multidomain cognitive training induced a significant improvement in the working memory and language abilities as well as depression symptoms and alleviated caregiver burden. Most of this cognitive enhancement persisted after six months (T2), with the exception of depression symptoms. Otherwise, a significant decline in attention abilities was reported, thus demonstrating a lack of effect in this function. Conclusions: Our results suggest that multidomain cognitive TNR is a suitable protocol for reducing some cognitive and behavioral alterations in patients with strokes, with a beneficial impact also on the caregivers’ burden distress management. Further RCTs are warranted to validate this new kind of approach. |
| format | Article |
| id | doaj-art-71fe7d9270254d25b69cd4aa3002dfda |
| institution | Kabale University |
| issn | 2076-3425 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj-art-71fe7d9270254d25b69cd4aa3002dfda2025-01-24T13:25:39ZengMDPI AGBrain Sciences2076-34252024-12-011511110.3390/brainsci15010011Application of Multidomain Cognitive Training in a Tele-Neurorehabilitation Setting for Treatment of Post-Stroke Cognitive DisordersMarianna Contrada0Loris Pignolo1Martina Vatrano2Caterina Pucci3Isabel Mantia4Federica Scarfone5Maria Quintieri6Antonio Cerasa7Gennarina Arabia8S.Anna Institute, 88900 Crotone, ItalyS.Anna Institute, 88900 Crotone, ItalyS.Anna Institute, 88900 Crotone, ItalyS.Anna Institute, 88900 Crotone, ItalyS.Anna Institute, 88900 Crotone, ItalyS.Anna Institute, 88900 Crotone, ItalyS.Anna Institute, 88900 Crotone, ItalyS.Anna Institute, 88900 Crotone, ItalyInstitute of Neurology, University Magna Graecia, 88100 Catanzaro, ItalyPurpose: Cognitive dysfunctions are still very common in the chronic phase of stroke when patients are discharged from neurorehabilitation centers. Even individuals who appear to have made a full clinical recovery may exhibit new deficiencies at home. Here, we present evidence of a novel kind of therapy at home aimed at contrasting the heterogenic evolution of stroke patients using a multidomain cognitive approach. Methods: Eighteen ischemic stroke patients were assessed in a within-subject longitudinal design (age 62.33 ± 11.1 years; eight men). Patients underwent the Tele-NeuroRehabilitation (TNR) multidomain cognitive training treatment using the Virtual Reality Rehabilitation System (VRRS) five times a week for 1 h sessions for four consecutive weeks. The protocol included the stimulation of specific cognitive functions, such as logical skills, praxis skills, attention, executive functions, memory, space time orientation and perception, and speech therapy. To determine neuropsychological changes, patients were evaluated before the sessions (T0), at the end of the sessions (T1), and after six months (T2). Results: The multidomain cognitive training induced a significant improvement in the working memory and language abilities as well as depression symptoms and alleviated caregiver burden. Most of this cognitive enhancement persisted after six months (T2), with the exception of depression symptoms. Otherwise, a significant decline in attention abilities was reported, thus demonstrating a lack of effect in this function. Conclusions: Our results suggest that multidomain cognitive TNR is a suitable protocol for reducing some cognitive and behavioral alterations in patients with strokes, with a beneficial impact also on the caregivers’ burden distress management. Further RCTs are warranted to validate this new kind of approach.https://www.mdpi.com/2076-3425/15/1/11Tele-NeuroRehabilitationmultidomain cognitive trainingstrokememorylanguagemood |
| spellingShingle | Marianna Contrada Loris Pignolo Martina Vatrano Caterina Pucci Isabel Mantia Federica Scarfone Maria Quintieri Antonio Cerasa Gennarina Arabia Application of Multidomain Cognitive Training in a Tele-Neurorehabilitation Setting for Treatment of Post-Stroke Cognitive Disorders Brain Sciences Tele-NeuroRehabilitation multidomain cognitive training stroke memory language mood |
| title | Application of Multidomain Cognitive Training in a Tele-Neurorehabilitation Setting for Treatment of Post-Stroke Cognitive Disorders |
| title_full | Application of Multidomain Cognitive Training in a Tele-Neurorehabilitation Setting for Treatment of Post-Stroke Cognitive Disorders |
| title_fullStr | Application of Multidomain Cognitive Training in a Tele-Neurorehabilitation Setting for Treatment of Post-Stroke Cognitive Disorders |
| title_full_unstemmed | Application of Multidomain Cognitive Training in a Tele-Neurorehabilitation Setting for Treatment of Post-Stroke Cognitive Disorders |
| title_short | Application of Multidomain Cognitive Training in a Tele-Neurorehabilitation Setting for Treatment of Post-Stroke Cognitive Disorders |
| title_sort | application of multidomain cognitive training in a tele neurorehabilitation setting for treatment of post stroke cognitive disorders |
| topic | Tele-NeuroRehabilitation multidomain cognitive training stroke memory language mood |
| url | https://www.mdpi.com/2076-3425/15/1/11 |
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