Characterization of tumor-infiltrating lymphocytes and their spatial distribution in triple-negative breast cancer

Characterization of tumor-infiltrating lymphocytes and their spatial distribution in triple-negative breast cancer

Abstract Background The tumor immune microenvironment, particularly tumor-infiltrating lymphocytes (TILs), plays a critical role in disease progression and treatment response in triple-negative breast cancers (TNBCs). This study was aimed to characterize the composition of TILs and investigate their...

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Main Authors: Eunkyung Han, Hye Yeon Choi, Hyun Jung Kwon, Yul Ri Chung, Hee-Chul Shin, Eun-Kyu Kim, Koung Jin Suh, Se Hyun Kim, Jee Hyun Kim, So Yeon Park
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Breast Cancer Research
Subjects:
Tumor infiltrating lymphocyte
Triple-negative breast cancer
Cytotoxic T lymphocyte
NK cell
Spatial distribution
Online Access:https://doi.org/10.1186/s13058-024-01932-4
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