Acid ion modification in a dialysis fluid

Apart from its main electrolytes – sodium, potassium, calcium and magnesium – a dialysis fluid (DF) contains a buffer for correction of acidosis. A small amount of acid is added to the DF to prevent calcium and magnesium precipitation. Acetic acid has traditionally been used for this purpose. Severa...

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Main Authors: I. L. Poz, A. G. Strokov
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2020-02-01
Series:Вестник трансплантологии и искусственных органов
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Online Access:https://journal.transpl.ru/vtio/article/view/1113
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author I. L. Poz
A. G. Strokov
author_facet I. L. Poz
A. G. Strokov
author_sort I. L. Poz
collection DOAJ
description Apart from its main electrolytes – sodium, potassium, calcium and magnesium – a dialysis fluid (DF) contains a buffer for correction of acidosis. A small amount of acid is added to the DF to prevent calcium and magnesium precipitation. Acetic acid has traditionally been used for this purpose. Several studies have shown that acetate ion, even in small concentrations, can cause a number of adverse events, such as low blood pressure, production of proinflammatory cytokines, etc. This literature review aims at considering alternative acidic components of DF, such as citric, hydrochloric, and succinic acids, as well as their advantages, possibilities and features of their use in wide clinical practice.
format Article
id doaj-art-71d62b51d20e43a095e5905afabb0c3b
institution Kabale University
issn 1995-1191
language Russian
publishDate 2020-02-01
publisher Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
record_format Article
series Вестник трансплантологии и искусственных органов
spelling doaj-art-71d62b51d20e43a095e5905afabb0c3b2025-08-20T03:59:52ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovВестник трансплантологии и искусственных органов1995-11912020-02-0121412913310.15825/1995-1191-2019-4-129-133832Acid ion modification in a dialysis fluidI. L. Poz0A. G. Strokov1Shumakov National Medical Research Center of Transplantology and Artificial OrgansShumakov National Medical Research Center of Transplantology and Artificial OrgansApart from its main electrolytes – sodium, potassium, calcium and magnesium – a dialysis fluid (DF) contains a buffer for correction of acidosis. A small amount of acid is added to the DF to prevent calcium and magnesium precipitation. Acetic acid has traditionally been used for this purpose. Several studies have shown that acetate ion, even in small concentrations, can cause a number of adverse events, such as low blood pressure, production of proinflammatory cytokines, etc. This literature review aims at considering alternative acidic components of DF, such as citric, hydrochloric, and succinic acids, as well as their advantages, possibilities and features of their use in wide clinical practice.https://journal.transpl.ru/vtio/article/view/1113dialysis fluidacetatecitratehydrochloridesuccinate
spellingShingle I. L. Poz
A. G. Strokov
Acid ion modification in a dialysis fluid
Вестник трансплантологии и искусственных органов
dialysis fluid
acetate
citrate
hydrochloride
succinate
title Acid ion modification in a dialysis fluid
title_full Acid ion modification in a dialysis fluid
title_fullStr Acid ion modification in a dialysis fluid
title_full_unstemmed Acid ion modification in a dialysis fluid
title_short Acid ion modification in a dialysis fluid
title_sort acid ion modification in a dialysis fluid
topic dialysis fluid
acetate
citrate
hydrochloride
succinate
url https://journal.transpl.ru/vtio/article/view/1113
work_keys_str_mv AT ilpoz acidionmodificationinadialysisfluid
AT agstrokov acidionmodificationinadialysisfluid