Relationship between MRI features and HIF-1α, GLUT1 and Ki-67 expression in pituitary adenoma with cystic degeneration

Relationship between MRI features and HIF-1α, GLUT1 and Ki-67 expression in pituitary adenoma with cystic degeneration

Abstract Background Pituitary adenomas (PAs) are prevalent tumors that often exhibit ischemia, hypoxia, and cystic transformations, impacting their prognosis. The relationship between cystic degeneration in PAs and the expressions of hypoxia-inducible factor-1α (HIF-1α), glucose transporter 1 (GLUT1...

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Bibliographic Details
Main Authors: Fangfang Zhang, Zhenhong Pan, Jianwu Wu, Yinxing Huang
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Medical Imaging
Subjects:
Pituitary adenoma
Fluid level
GLUT1
HIF-1α
Ki-67
Online Access:https://doi.org/10.1186/s12880-025-01574-8
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