INTERMOLECULAR INTERACTIONS IN NEURONAL FUNCTIONAL SYSTEMS
Neuronal synaptic contacts are among the basic elements that determine the plasticity of the nervous system. Changes in the efficiency of synaptic transmission mediate sensation, conduction of excitation, learning, and memory. Dendritic spines are the postsynaptic part of excitatory synapses in high...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders
2015-01-01
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| Series: | Вавиловский журнал генетики и селекции |
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| Online Access: | https://vavilov.elpub.ru/jour/article/view/186 |
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| author | A. L. Proskura I. A. Malachin T. A. Zapara I. I. Turnaev V. V. Suslov A. S. Ratuschnyak |
| author_facet | A. L. Proskura I. A. Malachin T. A. Zapara I. I. Turnaev V. V. Suslov A. S. Ratuschnyak |
| author_sort | A. L. Proskura |
| collection | DOAJ |
| description | Neuronal synaptic contacts are among the basic elements that determine the plasticity of the nervous system. Changes in the efficiency of synaptic transmission mediate sensation, conduction of excitation, learning, and memory. Dendritic spines are the postsynaptic part of excitatory synapses in higher divisions of mammalian brains. Protein–protein networks of spine microdomains form the functional system of neuronal synapses. Reconstruction of the conceptual model of molecular interactions has been performed. The model represents activity-dependent changes of the synaptic transmission efficiency, integration of excitation in the local dendritic network of a neuron, and prolonged maintenance of the new level of neurotransmission. |
| format | Article |
| id | doaj-art-71b320b6200e47cca4b74718d44b564e |
| institution | Kabale University |
| issn | 2500-3259 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders |
| record_format | Article |
| series | Вавиловский журнал генетики и селекции |
| spelling | doaj-art-71b320b6200e47cca4b74718d44b564e2025-02-01T09:58:00ZengSiberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and BreedersВавиловский журнал генетики и селекции2500-32592015-01-01174/1620628170INTERMOLECULAR INTERACTIONS IN NEURONAL FUNCTIONAL SYSTEMSA. L. Proskura0I. A. Malachin1T. A. Zapara2I. I. Turnaev3V. V. Suslov4A. S. Ratuschnyak5Design Technological Institute of Digital Techniques SB RAS, Novosibirsk, RussiaDesign Technological Institute of Digital Techniques SB RAS, Novosibirsk, RussiaDesign Technological Institute of Digital Techniques SB RAS, Novosibirsk, RussiaInstitute of Cytology and Genetics SB RAS, Novosibirsk, RussiaInstitute of Cytology and Genetics SB RAS, Novosibirsk, RussiaDesign Technological Institute of Digital Techniques SB RAS, Novosibirsk, RussiaNeuronal synaptic contacts are among the basic elements that determine the plasticity of the nervous system. Changes in the efficiency of synaptic transmission mediate sensation, conduction of excitation, learning, and memory. Dendritic spines are the postsynaptic part of excitatory synapses in higher divisions of mammalian brains. Protein–protein networks of spine microdomains form the functional system of neuronal synapses. Reconstruction of the conceptual model of molecular interactions has been performed. The model represents activity-dependent changes of the synaptic transmission efficiency, integration of excitation in the local dendritic network of a neuron, and prolonged maintenance of the new level of neurotransmission.https://vavilov.elpub.ru/jour/article/view/186synaptic plasticitylong-term potentiationglutamate receptors |
| spellingShingle | A. L. Proskura I. A. Malachin T. A. Zapara I. I. Turnaev V. V. Suslov A. S. Ratuschnyak INTERMOLECULAR INTERACTIONS IN NEURONAL FUNCTIONAL SYSTEMS Вавиловский журнал генетики и селекции synaptic plasticity long-term potentiation glutamate receptors |
| title | INTERMOLECULAR INTERACTIONS IN NEURONAL FUNCTIONAL SYSTEMS |
| title_full | INTERMOLECULAR INTERACTIONS IN NEURONAL FUNCTIONAL SYSTEMS |
| title_fullStr | INTERMOLECULAR INTERACTIONS IN NEURONAL FUNCTIONAL SYSTEMS |
| title_full_unstemmed | INTERMOLECULAR INTERACTIONS IN NEURONAL FUNCTIONAL SYSTEMS |
| title_short | INTERMOLECULAR INTERACTIONS IN NEURONAL FUNCTIONAL SYSTEMS |
| title_sort | intermolecular interactions in neuronal functional systems |
| topic | synaptic plasticity long-term potentiation glutamate receptors |
| url | https://vavilov.elpub.ru/jour/article/view/186 |
| work_keys_str_mv | AT alproskura intermolecularinteractionsinneuronalfunctionalsystems AT iamalachin intermolecularinteractionsinneuronalfunctionalsystems AT tazapara intermolecularinteractionsinneuronalfunctionalsystems AT iiturnaev intermolecularinteractionsinneuronalfunctionalsystems AT vvsuslov intermolecularinteractionsinneuronalfunctionalsystems AT asratuschnyak intermolecularinteractionsinneuronalfunctionalsystems |