Clinical and Genetic Review of Hereditary Acral Reticulate Pigmentary Disorders
Reticulated pigmentation is a unique pigmentary change caused by a heterogeneous group of hereditary and acquired disorders. This pigmentation is characterized by a mottled appearance, with lesions that vary in size and pigmentary content. This review discusses the hereditary group of the reticulate...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Dermatology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2017/3518568 |
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| author | H. Alshaikh F. Alsaif S. Aldukhi |
| author_facet | H. Alshaikh F. Alsaif S. Aldukhi |
| author_sort | H. Alshaikh |
| collection | DOAJ |
| description | Reticulated pigmentation is a unique pigmentary change caused by a heterogeneous group of hereditary and acquired disorders. This pigmentation is characterized by a mottled appearance, with lesions that vary in size and pigmentary content. This review discusses the hereditary group of the reticulated pigmentation disorders, such as dyschromatosis symmetrica hereditaria, dyschromatosis universalis hereditaria, and reticulate acropigmentation of Kitamura. The clinical presentation and histopathological features often overlap, making diagnosis difficult. However, each of these hereditary conditions possesses a unique genetic mutation, and genetic analysis is thus more useful in the diagnosis of these conditions. This article delivers an update regarding the clinical features, detailed histopathological description, and genetic information concerning hereditary reticulate pigmentary disorders and aims to provide useful background for use by clinical dermatologists and histopathologists when approaching this group of hereditary disorders. |
| format | Article |
| id | doaj-art-71ada559300f49acaf02ddcbb0cf4733 |
| institution | Kabale University |
| issn | 1687-6105 1687-6113 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Dermatology Research and Practice |
| spelling | doaj-art-71ada559300f49acaf02ddcbb0cf47332025-02-03T01:28:49ZengWileyDermatology Research and Practice1687-61051687-61132017-01-01201710.1155/2017/35185683518568Clinical and Genetic Review of Hereditary Acral Reticulate Pigmentary DisordersH. Alshaikh0F. Alsaif1S. Aldukhi2Department of Dermatology, College of Medicine, King Saud University, Riyadh, Saudi ArabiaDepartment of Dermatology, College of Medicine, King Saud University, Riyadh, Saudi ArabiaDepartment of Dermatology, College of Medicine, King Saud University, Riyadh, Saudi ArabiaReticulated pigmentation is a unique pigmentary change caused by a heterogeneous group of hereditary and acquired disorders. This pigmentation is characterized by a mottled appearance, with lesions that vary in size and pigmentary content. This review discusses the hereditary group of the reticulated pigmentation disorders, such as dyschromatosis symmetrica hereditaria, dyschromatosis universalis hereditaria, and reticulate acropigmentation of Kitamura. The clinical presentation and histopathological features often overlap, making diagnosis difficult. However, each of these hereditary conditions possesses a unique genetic mutation, and genetic analysis is thus more useful in the diagnosis of these conditions. This article delivers an update regarding the clinical features, detailed histopathological description, and genetic information concerning hereditary reticulate pigmentary disorders and aims to provide useful background for use by clinical dermatologists and histopathologists when approaching this group of hereditary disorders.http://dx.doi.org/10.1155/2017/3518568 |
| spellingShingle | H. Alshaikh F. Alsaif S. Aldukhi Clinical and Genetic Review of Hereditary Acral Reticulate Pigmentary Disorders Dermatology Research and Practice |
| title | Clinical and Genetic Review of Hereditary Acral Reticulate Pigmentary Disorders |
| title_full | Clinical and Genetic Review of Hereditary Acral Reticulate Pigmentary Disorders |
| title_fullStr | Clinical and Genetic Review of Hereditary Acral Reticulate Pigmentary Disorders |
| title_full_unstemmed | Clinical and Genetic Review of Hereditary Acral Reticulate Pigmentary Disorders |
| title_short | Clinical and Genetic Review of Hereditary Acral Reticulate Pigmentary Disorders |
| title_sort | clinical and genetic review of hereditary acral reticulate pigmentary disorders |
| url | http://dx.doi.org/10.1155/2017/3518568 |
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