Examining Emphysematous Pyelonephritis: A Case Study on Diagnosis and Outcomes

<b>Background</b>: Emphysematous pyelonephritis (EPN) is an infectious disease of the renal system caused by gas-producing microorganisms harboring the kidneys. Patients with diabetes mellitus (DM), an endocrine disease with hyperglycemia, are particularly susceptible to the EPN as their...

Full description

Saved in:
Bibliographic Details
Main Authors: Mahnoor Mahnoor, Syeda Aina Ali, Saira Nasir, Moiz Azmat, Hafiz Muhammad Umer Farooqi
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Emergency Care and Medicine
Subjects:
Online Access:https://www.mdpi.com/2813-7914/1/4/45
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832588629110685696
author Mahnoor Mahnoor
Syeda Aina Ali
Saira Nasir
Moiz Azmat
Hafiz Muhammad Umer Farooqi
author_facet Mahnoor Mahnoor
Syeda Aina Ali
Saira Nasir
Moiz Azmat
Hafiz Muhammad Umer Farooqi
author_sort Mahnoor Mahnoor
collection DOAJ
description <b>Background</b>: Emphysematous pyelonephritis (EPN) is an infectious disease of the renal system caused by gas-producing microorganisms harboring the kidneys. Patients with diabetes mellitus (DM), an endocrine disease with hyperglycemia, are particularly susceptible to the EPN as their immune system is compromised in fighting against infections. <b>Case Description</b>: We present a case of a 50-year-old female with a history of chronic diabetes and persistent hypertension. She presented with symptoms of pyrexia and flank pain. Following findings from ultrasound, she was advised to undergo computed tomographic (CT) scans that reveal air-filled hypodense areas at the upper and mid pole of the right kidney and in the renal pelvis of the right ureter, which confirms the class I EPN in the patient. Urine culture identifies <i>Escherica coli</i> as the causative agent for EPN. The patient was managed with third-generation antibiotics over two weeks, leading to full recovery without surgical intervention. <b>Discussion</b>: The availability of CT imaging makes early diagnosis and reduces mortality associated with EPN. Conservative medical management should be the initial treatment strategy for EPN. However, severe cases require immediate therapeutic action. In our case, the patient was treated with antibiotic therapy and recovered. <b>Conclusions</b>: CT scan seems to be the optimal diagnosis in patients with acute emphysematous pyelonephritis. Patients with EPN class I respond well to medical treatment with excellent outcomes.
format Article
id doaj-art-7193e972c42545288b4c4bf22c3db6d3
institution Kabale University
issn 2813-7914
language English
publishDate 2024-12-01
publisher MDPI AG
record_format Article
series Emergency Care and Medicine
spelling doaj-art-7193e972c42545288b4c4bf22c3db6d32025-01-24T13:29:57ZengMDPI AGEmergency Care and Medicine2813-79142024-12-011445446010.3390/ecm1040045Examining Emphysematous Pyelonephritis: A Case Study on Diagnosis and OutcomesMahnoor Mahnoor0Syeda Aina Ali1Saira Nasir2Moiz Azmat3Hafiz Muhammad Umer Farooqi4Turku PET Centre, Turku University Hospital, University of Turku, FI-20014 Turku, FinlandDepartment of Radiology, Cantonment General Hospital, Rawalpindi 46000, Punjab, PakistanDepartment of Radiology, Benazir Bhutto Hospital, Rawalpindi 46000, Punjab, PakistanDepartment of Medicine, Shifa Tameer-e-Millat University, Islamabad 44000, Islamabad, PakistanChildren’s Hospital of Orange County, Orange, CA 92868, USA<b>Background</b>: Emphysematous pyelonephritis (EPN) is an infectious disease of the renal system caused by gas-producing microorganisms harboring the kidneys. Patients with diabetes mellitus (DM), an endocrine disease with hyperglycemia, are particularly susceptible to the EPN as their immune system is compromised in fighting against infections. <b>Case Description</b>: We present a case of a 50-year-old female with a history of chronic diabetes and persistent hypertension. She presented with symptoms of pyrexia and flank pain. Following findings from ultrasound, she was advised to undergo computed tomographic (CT) scans that reveal air-filled hypodense areas at the upper and mid pole of the right kidney and in the renal pelvis of the right ureter, which confirms the class I EPN in the patient. Urine culture identifies <i>Escherica coli</i> as the causative agent for EPN. The patient was managed with third-generation antibiotics over two weeks, leading to full recovery without surgical intervention. <b>Discussion</b>: The availability of CT imaging makes early diagnosis and reduces mortality associated with EPN. Conservative medical management should be the initial treatment strategy for EPN. However, severe cases require immediate therapeutic action. In our case, the patient was treated with antibiotic therapy and recovered. <b>Conclusions</b>: CT scan seems to be the optimal diagnosis in patients with acute emphysematous pyelonephritis. Patients with EPN class I respond well to medical treatment with excellent outcomes.https://www.mdpi.com/2813-7914/1/4/45emphysematous pyelonephritistype 2 diabetescomputed tomography<i>Escherica coli</i>
spellingShingle Mahnoor Mahnoor
Syeda Aina Ali
Saira Nasir
Moiz Azmat
Hafiz Muhammad Umer Farooqi
Examining Emphysematous Pyelonephritis: A Case Study on Diagnosis and Outcomes
Emergency Care and Medicine
emphysematous pyelonephritis
type 2 diabetes
computed tomography
<i>Escherica coli</i>
title Examining Emphysematous Pyelonephritis: A Case Study on Diagnosis and Outcomes
title_full Examining Emphysematous Pyelonephritis: A Case Study on Diagnosis and Outcomes
title_fullStr Examining Emphysematous Pyelonephritis: A Case Study on Diagnosis and Outcomes
title_full_unstemmed Examining Emphysematous Pyelonephritis: A Case Study on Diagnosis and Outcomes
title_short Examining Emphysematous Pyelonephritis: A Case Study on Diagnosis and Outcomes
title_sort examining emphysematous pyelonephritis a case study on diagnosis and outcomes
topic emphysematous pyelonephritis
type 2 diabetes
computed tomography
<i>Escherica coli</i>
url https://www.mdpi.com/2813-7914/1/4/45
work_keys_str_mv AT mahnoormahnoor examiningemphysematouspyelonephritisacasestudyondiagnosisandoutcomes
AT syedaainaali examiningemphysematouspyelonephritisacasestudyondiagnosisandoutcomes
AT sairanasir examiningemphysematouspyelonephritisacasestudyondiagnosisandoutcomes
AT moizazmat examiningemphysematouspyelonephritisacasestudyondiagnosisandoutcomes
AT hafizmuhammadumerfarooqi examiningemphysematouspyelonephritisacasestudyondiagnosisandoutcomes