Seizure following the Use of the COX-2 Inhibitor Etoricoxib
We describe a case of epileptic seizures occurring after the use of a COX-2 inhibitor. A 61-year-old man was admitted to our department because of a generalized tonic-clonic seizure. EEG showed generalized slowdown of the activity. Neuroimaging and blood samples studies did not evidence alterations,...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Neurological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2017/1410759 |
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| _version_ | 1832550282099163136 |
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| author | Valentina Arnao Marianna Riolo Brigida Fierro Paolo Aridon |
| author_facet | Valentina Arnao Marianna Riolo Brigida Fierro Paolo Aridon |
| author_sort | Valentina Arnao |
| collection | DOAJ |
| description | We describe a case of epileptic seizures occurring after the use of a COX-2 inhibitor. A 61-year-old man was admitted to our department because of a generalized tonic-clonic seizure. EEG showed generalized slowdown of the activity. Neuroimaging and blood samples studies did not evidence alterations, but a careful pharmacological history revealed that the patient had taken the COX-2 inhibitor etoricoxib to treat lumbago few days before the onset of clinical symptoms. No seizures were reported after etoricoxib discontinuation and an EEG resulted to be normal two months after this. Conclusion. Knowing the pharmacological history of a patient is important for understanding the clinical presentation and selecting appropriate treatment. This is, to the best of our knowledge, the first reported case of generalized seizures associated with the use of COX-2 inhibitors. |
| format | Article |
| id | doaj-art-71857775e67b4ec8850e2e63c9f24c4c |
| institution | Kabale University |
| issn | 2090-6668 2090-6676 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Neurological Medicine |
| spelling | doaj-art-71857775e67b4ec8850e2e63c9f24c4c2025-02-03T06:07:06ZengWileyCase Reports in Neurological Medicine2090-66682090-66762017-01-01201710.1155/2017/14107591410759Seizure following the Use of the COX-2 Inhibitor EtoricoxibValentina Arnao0Marianna Riolo1Brigida Fierro2Paolo Aridon3Dipartimento di Biomedicina Sperimentale e Neuroscienze Cliniche, Università degli Studi di Palermo, Palermo, ItalyDipartimento di Biomedicina Sperimentale e Neuroscienze Cliniche, Università degli Studi di Palermo, Palermo, ItalyDipartimento di Biomedicina Sperimentale e Neuroscienze Cliniche, Università degli Studi di Palermo, Palermo, ItalyDipartimento di Biomedicina Sperimentale e Neuroscienze Cliniche, Università degli Studi di Palermo, Palermo, ItalyWe describe a case of epileptic seizures occurring after the use of a COX-2 inhibitor. A 61-year-old man was admitted to our department because of a generalized tonic-clonic seizure. EEG showed generalized slowdown of the activity. Neuroimaging and blood samples studies did not evidence alterations, but a careful pharmacological history revealed that the patient had taken the COX-2 inhibitor etoricoxib to treat lumbago few days before the onset of clinical symptoms. No seizures were reported after etoricoxib discontinuation and an EEG resulted to be normal two months after this. Conclusion. Knowing the pharmacological history of a patient is important for understanding the clinical presentation and selecting appropriate treatment. This is, to the best of our knowledge, the first reported case of generalized seizures associated with the use of COX-2 inhibitors.http://dx.doi.org/10.1155/2017/1410759 |
| spellingShingle | Valentina Arnao Marianna Riolo Brigida Fierro Paolo Aridon Seizure following the Use of the COX-2 Inhibitor Etoricoxib Case Reports in Neurological Medicine |
| title | Seizure following the Use of the COX-2 Inhibitor Etoricoxib |
| title_full | Seizure following the Use of the COX-2 Inhibitor Etoricoxib |
| title_fullStr | Seizure following the Use of the COX-2 Inhibitor Etoricoxib |
| title_full_unstemmed | Seizure following the Use of the COX-2 Inhibitor Etoricoxib |
| title_short | Seizure following the Use of the COX-2 Inhibitor Etoricoxib |
| title_sort | seizure following the use of the cox 2 inhibitor etoricoxib |
| url | http://dx.doi.org/10.1155/2017/1410759 |
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