Diagnostic Sensitivity of Different Reference Bodies When Using Scheimpflug Tomography in a Myopic Population with Keratoconus
Purpose. To establish which reference body offers the greatest sensitivity in keratoconus (KC) diagnosis, obtain normative data for the myopic population with toric ellipsoid reference bodies, and determine the cutoff points for a population with KC. Methods. A retrospective, observational study of...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2019/2593404 |
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| author | Daniel Garcerant Ignacio Jiménez-Alfaro Nicolás Alejandre |
| author_facet | Daniel Garcerant Ignacio Jiménez-Alfaro Nicolás Alejandre |
| author_sort | Daniel Garcerant |
| collection | DOAJ |
| description | Purpose. To establish which reference body offers the greatest sensitivity in keratoconus (KC) diagnosis, obtain normative data for the myopic population with toric ellipsoid reference bodies, and determine the cutoff points for a population with KC. Methods. A retrospective, observational study of the entire Scheimpflug tomographer database of the Fundación Jiménez Díaz in Madrid was conducted to identify a normal myopic and a KC myopic population. Three different reference bodies were tested on all patients: best fit sphere (BFS), best fit toric ellipsoid with fixed eccentricity (BFTEFE), and best fit toric ellipsoid (BFTE). Anterior and posterior elevation measurements at the apex and thinnest point were recorded, as well as the root mean square of posterior elevations (RMS-P). Normative data were extracted, and receiver operating characteristic (ROC) curves were generated to obtain cutoff points between the normal and KC population. Results. A total of 301 eyes were included, comprising 219 normal myopic and 82 myopic KC eyes. BFS and BFTEFE produced the best results when measuring posterior elevation at the thinnest point. BFTE had better sensitivity with the RMS-P. From all measurements, best sensitivity (100%) was achieved with a cutoff point of 8 μm of posterior elevation at the thinnest point using the BFTEFE. BFTE was found to hide the cone in certain patients. Conclusions. Posterior elevation measured at the thinnest point with a BFTEFE is the best-performing parameter and, therefore, is recommended to discriminate between normal and KC patients within a myopic population. |
| format | Article |
| id | doaj-art-71848892628842e19c1daa8d016e83d0 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-71848892628842e19c1daa8d016e83d02025-02-03T01:02:13ZengWileyJournal of Ophthalmology2090-004X2090-00582019-01-01201910.1155/2019/25934042593404Diagnostic Sensitivity of Different Reference Bodies When Using Scheimpflug Tomography in a Myopic Population with KeratoconusDaniel Garcerant0Ignacio Jiménez-Alfaro1Nicolás Alejandre2Fundación Jiménez Díaz, Madrid, SpainFundación Jiménez Díaz, Madrid, SpainFundación Jiménez Díaz, Madrid, SpainPurpose. To establish which reference body offers the greatest sensitivity in keratoconus (KC) diagnosis, obtain normative data for the myopic population with toric ellipsoid reference bodies, and determine the cutoff points for a population with KC. Methods. A retrospective, observational study of the entire Scheimpflug tomographer database of the Fundación Jiménez Díaz in Madrid was conducted to identify a normal myopic and a KC myopic population. Three different reference bodies were tested on all patients: best fit sphere (BFS), best fit toric ellipsoid with fixed eccentricity (BFTEFE), and best fit toric ellipsoid (BFTE). Anterior and posterior elevation measurements at the apex and thinnest point were recorded, as well as the root mean square of posterior elevations (RMS-P). Normative data were extracted, and receiver operating characteristic (ROC) curves were generated to obtain cutoff points between the normal and KC population. Results. A total of 301 eyes were included, comprising 219 normal myopic and 82 myopic KC eyes. BFS and BFTEFE produced the best results when measuring posterior elevation at the thinnest point. BFTE had better sensitivity with the RMS-P. From all measurements, best sensitivity (100%) was achieved with a cutoff point of 8 μm of posterior elevation at the thinnest point using the BFTEFE. BFTE was found to hide the cone in certain patients. Conclusions. Posterior elevation measured at the thinnest point with a BFTEFE is the best-performing parameter and, therefore, is recommended to discriminate between normal and KC patients within a myopic population.http://dx.doi.org/10.1155/2019/2593404 |
| spellingShingle | Daniel Garcerant Ignacio Jiménez-Alfaro Nicolás Alejandre Diagnostic Sensitivity of Different Reference Bodies When Using Scheimpflug Tomography in a Myopic Population with Keratoconus Journal of Ophthalmology |
| title | Diagnostic Sensitivity of Different Reference Bodies When Using Scheimpflug Tomography in a Myopic Population with Keratoconus |
| title_full | Diagnostic Sensitivity of Different Reference Bodies When Using Scheimpflug Tomography in a Myopic Population with Keratoconus |
| title_fullStr | Diagnostic Sensitivity of Different Reference Bodies When Using Scheimpflug Tomography in a Myopic Population with Keratoconus |
| title_full_unstemmed | Diagnostic Sensitivity of Different Reference Bodies When Using Scheimpflug Tomography in a Myopic Population with Keratoconus |
| title_short | Diagnostic Sensitivity of Different Reference Bodies When Using Scheimpflug Tomography in a Myopic Population with Keratoconus |
| title_sort | diagnostic sensitivity of different reference bodies when using scheimpflug tomography in a myopic population with keratoconus |
| url | http://dx.doi.org/10.1155/2019/2593404 |
| work_keys_str_mv | AT danielgarcerant diagnosticsensitivityofdifferentreferencebodieswhenusingscheimpflugtomographyinamyopicpopulationwithkeratoconus AT ignaciojimenezalfaro diagnosticsensitivityofdifferentreferencebodieswhenusingscheimpflugtomographyinamyopicpopulationwithkeratoconus AT nicolasalejandre diagnosticsensitivityofdifferentreferencebodieswhenusingscheimpflugtomographyinamyopicpopulationwithkeratoconus |