Focal Segmental Glomerulosclerosis in Waldenström’s Macroglobulinemia
Renal involvement in Waldenström’s macroglobulinemia is a rare manifestation. Although most renal involvement is due to monoclonal immune deposits, pathology can also be unrelated to it. Here, we describe a 68-year-old female with a history of Waldenström’s macroglobulinemia who presented with gener...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-01-01
|
| Series: | Case Reports in Nephrology |
| Online Access: | http://dx.doi.org/10.1155/2020/8895705 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832550839978295296 |
|---|---|
| author | Akshee Batra Shatha Herz Allah Bijin Thajudeen |
| author_facet | Akshee Batra Shatha Herz Allah Bijin Thajudeen |
| author_sort | Akshee Batra |
| collection | DOAJ |
| description | Renal involvement in Waldenström’s macroglobulinemia is a rare manifestation. Although most renal involvement is due to monoclonal immune deposits, pathology can also be unrelated to it. Here, we describe a 68-year-old female with a history of Waldenström’s macroglobulinemia who presented with generalized edema and nephrotic range proteinuria. A renal biopsy showed findings consistent with focal segmental glomerulosclerosis. Treatment with oral prednisone leads to the resolution of proteinuria. This case highlights the importance of identifying pathology that might not be directly related to monoclonal gammopathy, which could have implications on the management. |
| format | Article |
| id | doaj-art-7161c9adc3f6424cb0ed63c818d6c083 |
| institution | Kabale University |
| issn | 2090-6641 2090-665X |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Nephrology |
| spelling | doaj-art-7161c9adc3f6424cb0ed63c818d6c0832025-02-03T06:05:41ZengWileyCase Reports in Nephrology2090-66412090-665X2020-01-01202010.1155/2020/88957058895705Focal Segmental Glomerulosclerosis in Waldenström’s MacroglobulinemiaAkshee Batra0Shatha Herz Allah1Bijin Thajudeen2Department of Nephrology, Banner University of Arizona Medical Center, 1501 North Campbell Ave, Tucson, AZ, USADepartment of Nephrology, Banner University of Arizona Medical Center, 1501 North Campbell Ave, Tucson, AZ, USADepartment of Nephrology, Banner University of Arizona Medical Center, 1501 North Campbell Ave, Tucson, AZ, USARenal involvement in Waldenström’s macroglobulinemia is a rare manifestation. Although most renal involvement is due to monoclonal immune deposits, pathology can also be unrelated to it. Here, we describe a 68-year-old female with a history of Waldenström’s macroglobulinemia who presented with generalized edema and nephrotic range proteinuria. A renal biopsy showed findings consistent with focal segmental glomerulosclerosis. Treatment with oral prednisone leads to the resolution of proteinuria. This case highlights the importance of identifying pathology that might not be directly related to monoclonal gammopathy, which could have implications on the management.http://dx.doi.org/10.1155/2020/8895705 |
| spellingShingle | Akshee Batra Shatha Herz Allah Bijin Thajudeen Focal Segmental Glomerulosclerosis in Waldenström’s Macroglobulinemia Case Reports in Nephrology |
| title | Focal Segmental Glomerulosclerosis in Waldenström’s Macroglobulinemia |
| title_full | Focal Segmental Glomerulosclerosis in Waldenström’s Macroglobulinemia |
| title_fullStr | Focal Segmental Glomerulosclerosis in Waldenström’s Macroglobulinemia |
| title_full_unstemmed | Focal Segmental Glomerulosclerosis in Waldenström’s Macroglobulinemia |
| title_short | Focal Segmental Glomerulosclerosis in Waldenström’s Macroglobulinemia |
| title_sort | focal segmental glomerulosclerosis in waldenstrom s macroglobulinemia |
| url | http://dx.doi.org/10.1155/2020/8895705 |
| work_keys_str_mv | AT aksheebatra focalsegmentalglomerulosclerosisinwaldenstromsmacroglobulinemia AT shathaherzallah focalsegmentalglomerulosclerosisinwaldenstromsmacroglobulinemia AT bijinthajudeen focalsegmentalglomerulosclerosisinwaldenstromsmacroglobulinemia |