Adenoid Cystic Carcinoma of the Submandibular Gland, Locoregional Recurrence, and a Solitary Liver Metastasis More Than 30 Years Since Primary Diagnosis
Adenoid cystic carcinoma (ACC) is a relatively rare tumour of the salivary glands, accounting for approximately 5%–10% of all salivary gland tumours. An important feature of ACCs is the long clinical course with a high rate of distant metastases. The preferential sites of metastases are the lung and...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2014-01-01
|
| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2014/581823 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832562741992226816 |
|---|---|
| author | A. Coupland A. Sewpaul A. Darne S. White |
| author_facet | A. Coupland A. Sewpaul A. Darne S. White |
| author_sort | A. Coupland |
| collection | DOAJ |
| description | Adenoid cystic carcinoma (ACC) is a relatively rare tumour of the salivary glands, accounting for approximately 5%–10% of all salivary gland tumours. An important feature of ACCs is the long clinical course with a high rate of distant metastases. The preferential sites of metastases are the lung and bone, followed by the brain and liver. Most liver metastases are derived from nonparotid ACCs, and the presentation is often related to local recurrence or metastases to other organs. Solitary metastases to the liver are rare and optimal management is unknown. We present the case of a metastatic ACC to the liver with primary disease presentation at a young age. We discuss our management and other potential treatment modalities. |
| format | Article |
| id | doaj-art-715fcc1bb71e451fb1a9d217079d001f |
| institution | Kabale University |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Surgery |
| spelling | doaj-art-715fcc1bb71e451fb1a9d217079d001f2025-02-03T01:21:53ZengWileyCase Reports in Surgery2090-69002090-69192014-01-01201410.1155/2014/581823581823Adenoid Cystic Carcinoma of the Submandibular Gland, Locoregional Recurrence, and a Solitary Liver Metastasis More Than 30 Years Since Primary DiagnosisA. Coupland0A. Sewpaul1A. Darne2S. White3Department of HPB and Transplant Surgery, Freeman Hospital, Newcastle upon Tyne NE7 7DN, UKDepartment of HPB and Transplant Surgery, Freeman Hospital, Newcastle upon Tyne NE7 7DN, UKDepartment of Histopathology, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UKDepartment of HPB and Transplant Surgery, Freeman Hospital, Newcastle upon Tyne NE7 7DN, UKAdenoid cystic carcinoma (ACC) is a relatively rare tumour of the salivary glands, accounting for approximately 5%–10% of all salivary gland tumours. An important feature of ACCs is the long clinical course with a high rate of distant metastases. The preferential sites of metastases are the lung and bone, followed by the brain and liver. Most liver metastases are derived from nonparotid ACCs, and the presentation is often related to local recurrence or metastases to other organs. Solitary metastases to the liver are rare and optimal management is unknown. We present the case of a metastatic ACC to the liver with primary disease presentation at a young age. We discuss our management and other potential treatment modalities.http://dx.doi.org/10.1155/2014/581823 |
| spellingShingle | A. Coupland A. Sewpaul A. Darne S. White Adenoid Cystic Carcinoma of the Submandibular Gland, Locoregional Recurrence, and a Solitary Liver Metastasis More Than 30 Years Since Primary Diagnosis Case Reports in Surgery |
| title | Adenoid Cystic Carcinoma of the Submandibular Gland, Locoregional Recurrence, and a Solitary Liver Metastasis More Than 30 Years Since Primary Diagnosis |
| title_full | Adenoid Cystic Carcinoma of the Submandibular Gland, Locoregional Recurrence, and a Solitary Liver Metastasis More Than 30 Years Since Primary Diagnosis |
| title_fullStr | Adenoid Cystic Carcinoma of the Submandibular Gland, Locoregional Recurrence, and a Solitary Liver Metastasis More Than 30 Years Since Primary Diagnosis |
| title_full_unstemmed | Adenoid Cystic Carcinoma of the Submandibular Gland, Locoregional Recurrence, and a Solitary Liver Metastasis More Than 30 Years Since Primary Diagnosis |
| title_short | Adenoid Cystic Carcinoma of the Submandibular Gland, Locoregional Recurrence, and a Solitary Liver Metastasis More Than 30 Years Since Primary Diagnosis |
| title_sort | adenoid cystic carcinoma of the submandibular gland locoregional recurrence and a solitary liver metastasis more than 30 years since primary diagnosis |
| url | http://dx.doi.org/10.1155/2014/581823 |
| work_keys_str_mv | AT acoupland adenoidcysticcarcinomaofthesubmandibularglandlocoregionalrecurrenceandasolitarylivermetastasismorethan30yearssinceprimarydiagnosis AT asewpaul adenoidcysticcarcinomaofthesubmandibularglandlocoregionalrecurrenceandasolitarylivermetastasismorethan30yearssinceprimarydiagnosis AT adarne adenoidcysticcarcinomaofthesubmandibularglandlocoregionalrecurrenceandasolitarylivermetastasismorethan30yearssinceprimarydiagnosis AT swhite adenoidcysticcarcinomaofthesubmandibularglandlocoregionalrecurrenceandasolitarylivermetastasismorethan30yearssinceprimarydiagnosis |