Per1/Per2 double knockout transcriptome analysis reveals circadian regulation of hepatic lipid metabolism

Per1/Per2 double knockout transcriptome analysis reveals circadian regulation of hepatic lipid metabolism

Scope: Circadian disorder and high-fat diet (HFD) can disturb lipid metabolism homeostasis and may promote the development of various metabolic diseases. The relationship between them is of great concern. This study aimed to explore the effects of Per1/Per2 double knockout (DKO) on hepatic lipid met...

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Bibliographic Details
Main Authors: Yiran Bu, Si Chen, Mengcheng Ruan, Libang Wu, Hualin Wang, Na Li, Xiuju Zhao, Xiaoli Yu, Zhiguo Liu
Format: Article
Language:English
Published: Tsinghua University Press 2023-09-01
Series:Food Science and Human Wellness
Subjects:
DHA
High-fat diet
Lipid metabolism
Per1/Per2
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2213453023000344
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